Does hydrocortisone interact with other medications?

Does hydrocortisone interact with other medications?

Some products that may interact with this drug are: aldesleukin, mifepristone, other drugs that can cause bleeding/bruising (such as antiplatelet drugs like clopidogrel, NSAIDs like ibuprofen/naproxen, “blood thinners” like warfarin/dabigatran). Aspirin can increase the risk of bleeding when used with this medication.

What IV drugs are incompatible?

Type of intravenous drug administration involved in incompatibilities….Table 2.

Drug incompatibilities N (%)
Hydrocortisone x midazolam 24 (8.9)
Cefepime x midazolam 14 (5.2)
Hydrocortisone x vancomycin 14 (5.2)
Cefepime x vancomycin 12 (4.4)

How do I know if IV meds are compatible?

Drug combinations are tested for compatibility in solution. Incompatibility is present when visible or electronically-determined precipitates, particulates, haziness, turbidity, color, or gas evolution are detected. A 10% or greater loss of intact drug within 24 hours is also considered evidence of incompatibility.

What are the contraindications of hydrocortisone?

Who should not take HYDROCORTISONE?

  • inactive tuberculosis.
  • herpes simplex infection of the eye.
  • an infection due to a fungus.
  • intestinal infection caused by the roundworm Strongyloides.
  • pheochromocytoma.
  • a condition with low thyroid hormone levels.
  • diabetes.
  • insufficiency of the hypothalamus and pituitary gland.

Can you take Tramadol with hydrocortisone?

You should not take hydrocodone and tramadol together because doing this can lead to serious side effects like seizures, respiratory depression, coma, and even death. Taking these two together also increases your risk of overdose.

Which of the following factors may affect IV compatibility?

The following factors can affect the chemical compatibility of an I.V….Factors affecting compatibility

  • order of mixing.
  • drug concentration.
  • contact time.
  • temperature.
  • pH.

What is incompatible with LR?

Eight drugs, ciprofloxacin, cyclosporine, diazepam, ketamine, lorazepam, nitroglycerin, phenytoin, and propofol, were found to be incompatible and should not be administered with LR.

How would the nurse know if the drug to be infused is compatible with the IV solution?

Generally, to avoid incompatibility, drugs and solutions that are to be mixed should have similar pH values. The pH of each I.V. solution is listed on the manufacturer’s label, and the pH of each drug is provided in the package insert.

Why is hydrocortisone given IV?

Hydrocortisone is used to treat certain medical conditions, such as inflammation (swelling), severe allergic reactions, kidney diseases, adrenal problems, arthritis, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, and ulcerative colitis.

When should IV hydrocortisone be administered?

IV: 100 mg IV bolus given immediately, followed by 25 to 75 mg IV every 6 hours or 200 mg/24 hours as a continuous IV infusion for the first 24 hours. Reassess patient after the initial 24 hours; if clinical status has improved may begin gradually tapering the dose.

Can zosyn and LR run together?

ZOSYN Injection is to be administered using sterile equipment, after thawing to room temperature. ZOSYN containing EDTA is compatible for co-administration via a Y-site intravenous tube with Lactated Ringer’s injection, USP. Do not add supplementary medication. Unused portions of ZOSYN should be discarded.

What medications interact with lactated ringers?

Drug Interactions

  • Alacepril.
  • Amiloride.
  • Baloxavir Marboxil.
  • Benazepril.
  • Bictegravir.
  • Canrenoate.
  • Captopril.
  • Cilazapril.

What are the side effects of hydrocortisone for children?

Tell your doctor if your child is not growing at a normal rate while using hydrocortisone. Common side effects may include: thinning skin, bruising or discoloration; increased sweating; stomach bloating; changes in your menstrual periods; increased appetite, weight gain; headache, dizziness; or.

What drugs can affect hydrocortisone?

Many drugs can affect hydrocortisone, especially: aspirin or an NSAID (nonsteroidal anti-inflammatory drug) such as ibuprofen, naproxen, celecoxib, indomethacin, Advil, Aleve, Motrin, and others. This list is not complete and many other drugs may affect hydrocortisone.

Can hydrocortisone be given by injection?

Hydrocortisone is usually given by injection if you are unable to take the medicine by mouth. Your doctor will need to check your progress on a regular basis. Your dose needs may change if you have a serious illness, fever or infection, surgery or a medical emergency. Tell your doctor about any such situation that affects you.

What is the dilution of hydrocortisone?

Dilution. For IV infusion, further dilute the reconstituted hydrocortisone sodium succinate solutions with 5% dextrose, 0.9% sodium chloride, or 5% dextrose in 0.9% sodium chloride injection to a concentration of 0.1–1 mg/mL. a. Rate of Administration