Table of Contents
What does a positive anti-dsDNA mean?
The presence of anti-dsDNA antibodies often suggests more serious lupus, such as lupus nephritis (kidney lupus). When the disease is active, especially in the kidneys, high amounts of anti-DNA antibodies are usually present.
What is anti-dsDNA normal range?
Reference Range: <30.0 IU/mL Negative 30.0 – 75.0 IU/mL Borderline >75.0 IU/mL Positive Negative is considered normal.
What can cause high anti-dsDNA?
A high level of anti-dsDNA in the blood is strongly associated with lupus and is often significantly increased during or just prior to a flare-up. When the anti-dsDNA is positive and the person tested has other clinical signs and symptoms associated with lupus, it means that the person tested likely has lupus.
Can you have anti-dsDNA and not have lupus?
The anti-dsDNA test is fairly specific for lupus; however, only 65-85% of people with lupus may be positive; that is, a negative anti-dsDNA does not rule out lupus. If a person has a positive ANA, an anti-dsDNA test may be used to distinguish lupus from other autoimmune disorders that have similar signs and symptoms.
What does a positive anti dsDNA test mean?
Anti-Double Stranded DNA (Anti-dsDNA) The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE). That’s because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders other than SLE. A strongly positive anti-dsDNA antibody test makes it very likely that a person has SLE.
What is an anti-dsDNA test for SLE?
Anti-Double Stranded DNA (Anti-dsDNA) The anti-dsDNA (anti-double stranded DNA) antibody test is a blood test that looks for antibodies to double stranded DNA. The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE) because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders.
What is anti double stranded DNA antibody test?
Anti-Double Stranded DNA (Anti-dsDNA) The anti-dsDNA (anti-double stranded DNA) antibody test is a blood test that looks for antibodies to double stranded DNA. The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE).
What does low anti-dsDNA mean in lupus?
In the evaluation of someone with lupus nephritis, a high level (titer) of anti-dsDNA is generally associated with ongoing inflammation and damage to the kidneys. A very low level of anti-dsDNA is considered negative but does not exclude a diagnosis of lupus. Only about 60-85% of those with lupus will have anti-dsDNA.