Table of Contents
What are the causes and effects of a frameshift mutation?
Usually, frameshift mutations occur as caused by a mutational error during DNA repair or replication. They can also occur by exposure to acridine dyes, which are capable of inducing frameshift mutations.
What is frameshift mutation in biology?
Listen to pronunciation. (FRAYM-shift myoo-TAY-shun) An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
What causes frameshift mutations What are the possible effects of these types of mutations quizlet?
The addition of an extra nucleotide to a DNA sequence that causes a frameshift mutation which usually produces a malfunctioning protein. The deletion of a nucleotide in a DNA sequence that causes a frameshift mutation which usually produces a malfunctioning protein.
When would mutation not be harmful?
The vast majority of mutations are NEUTRAL. They have no effect on the phenotype. That most mutations are harmful is a creationist myth. Second, “beneficial” or “harmful” are in relation to the environment. Only about 2.6 per thousand mutations are absolutely harmful; they cause the death or significant harm to the organism.
When is mutation most likely to occur?
Mutations can occur during DNA replication if errors are made and not corrected in time. Mutations can also occur as the result of exposure to environmental factors such as smoking, sunlight and radiation. Often cells can recognize any potentially mutation-causing damage and repair it before it becomes a fixed mutation.
What happens when a nonsense mutation occurs?
Thus, nonsense mutations occur when a premature nonsense or stop codon is introduced in the DNA sequence. When the mutated sequence is translated into a protein, the resulting protein is incomplete and shorter than normal. Consequently, most nonsense mutations result in nonfunctional proteins.
When do mutations become fatal?
When a mutation alters a protein that plays a critical role in the body, it can disrupt normal development or cause a medical condition. A condition caused by mutations in one or more genes is called a genetic disorder. In some cases, gene mutations are so severe that they prevent an embryo from surviving until birth.