Table of Contents
What is aminophylline drug used for?
Aminophylline injection is used together with other medicines to treat the acute symptoms of asthma, bronchitis, emphysema, and other lung diseases in a hospital setting. Aminophylline belongs to a group of medicines known as bronchodilators.
What should be monitored when taking aminophylline?
Patients receiving aminophylline require monitoring for CNS effects, respiratory rate, arterial blood gasses, and serum theophylline concentrations. Clinicians must measure serum concentrations before initiating a loading dose in a person who has taken theophylline in the last 24 hours.
When do you give IV aminophylline?
This policy offers advice on intravenous aminophylline dosing and monitoring in patients with life threatening asthma. Intravenous aminophylline should only be prescribed in acute severe asthma unresponsive to nebulised bronchodilators and life threatening asthma.
What are the side effects of the drug aminophylline?
Aminophylline side effects fast or irregular heartbeats; a seizure; high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or. low potassium level–leg cramps, constipation, irregular heartbeats, fluttering in your chest, numbness or tingling, muscle weakness or limp feeling.
Can aminophylline cause drowsiness?
Aminophylline may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Is aminophylline an emergency drug?
Aminophylline is a bronchodilator that is used with other medications to treat sudden worsening of the symptoms of asthma, bronchitis, or emphysema. Aminophylline may also be used for purposes not listed in this medication guide.
Can aminophylline be given IV push?
Aminophylline Injection, USP is a sterile, nonpyrogenic solution of aminophylline in water for injection. Aminophylline (dihydrate) is approximately 79% of anhydrous theophylline by weight. Aminophylline Injection is administered by slow intravenous injection or diluted and administered by intravenous infusion.
Does aminophylline cause insomnia?
General. The most common adverse events with peak serum theophylline levels under 20 mcg/mL are transient caffeine-like events such as nausea, vomiting, headache, and insomnia.
Why is IV aminophylline given slowly?
Intravenous Aminophylline must be administered very slowly to prevent dangerous central nervous system and cardiovascular side-effects due to direct stimulating effect of Aminophylline.
What are the side effects of aminophylline?
They cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More serious effects are haematemesis, convulsions, and supraventricular and ventricular arrhythmias. Severe hypokalaemia may develop rapidly.
What does aminophylline do to the heart?
Aminophylline produced consistent and significant increases in cardiac output and significant decreases in left ventricular end-diastolic pressure, pulmonary artery pressures and right ventricular end-diastolic pressure.
Does aminophylline cause drowsiness?
Is it safe to use aminophylline?
Aminophylline should be used with caution in patients with peptic ulcer, hyperthyroidism, glaucoma, diabetes mellitus, severe hypoxaemia, hypertension and compromised cardiac or circulatory function, as these conditions may be exacerbated.
Is aminophylline a dihydrate?
Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline.
What is aminophylline used to treat?
Aminophylline is indicated as an adjunct to inhaled beta-2 selective agonists and systemic corticosteroids to treat acute exacerbations of the symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases, e.g., emphysema and chronic bronchitis. [1] Non-FDA Approved Uses
What is the difference between ethylenediamine and aminophylline?
The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor.
Is aminophylline a phosphodiesterase inhibitor?
Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor. Intravenous aminophylline can be used for acute exacerbation of symptoms and reversible airway obstruction in asthma and other chronic lung disease such as COPD, emphysema and chronic bronchitis.