Table of Contents
What is epanutin 100mg used for?
This medicine contains phenytoin, which is one of a group of medicines called anti-epileptic drugs; these medicines are used to treat epilepsy. Epanutin can be used to control a variety of epileptic conditions, to control or prevent seizures during or after brain surgery or severe head injury.
Is phenytoin and epanutin the same?
Epanutin oral suspension and infatabs both contain the active ingredient phenytoin, which is a type of medicine called an anticonvulsant. Phenytoin is also available without a brand name, ie as the generic medicine.
How do you give phenytoin 100mg IV?
Phenytoin IV administration
- Give phenytoin over 30-40 minutes (rate <50mg/minute).
- Ideally, administer undiluted via a syringe pump through a large gauge needle or IV catheter into a large forearm vein.
How do you take IV epanutin?
For IV infusion, Pro-Epanutin should be diluted in 5% glucose or 0.9% sodium chloride solution. The concentration should range from 1.5 to 25 mg PE/mL. Because of the risk of hypotension, the recommended rate of administration by IV infusion in routine clinical settings is 50-100 mg PE/minute.
What are the side effects of epanutin?
Side effects of phenytoin
- Headaches. Make sure you rest and drink plenty of fluids.
- Feeling drowsy, sleepy or dizzy. As your body gets used to phenytoin, these side effects should wear off.
- Feeling nervous, unsteady or shaky.
- Feeling or being sick (nausea or vomiting)
- Constipation.
- Sore or swollen gums.
What is the difference between Dilantin and phenytoin?
Phenytoin (FEN-ih-toe-in) is the generic name (non–brand name) of a widely used seizure medicine. Common brand names for this type of medicine include Dilantin, but it is also sold using the name phenytoin or phenytoin sodium.
How do you mix phenytoin IV?
For administration by intravenous infusion phenytoin injection should be diluted in 50 – 100 ml of normal saline, and the final concentration of phenytoin in the solution should not exceed 10 mg/ml, the infusion mixture should not be refrigerated.
How do you give IV phenytoin?
Phenytoin Injection BP should be injected slowly and directly into a large vein through a large-gauge needle or intravenous catheter. It must be administered slowly. Intravenous administration should not exceed 50 mg/minute in adults.
What is a phenytoin equivalent?
DESCRIPTION. CEREBYX® (fosphenytoin sodium injection) is a prodrug intended for parenteral administration; its active metabolite is phenytoin. 1.5 mg of fosphenytoin sodium is equivalent to 1 mg phenytoin sodium, and is referred to as 1 mg phenytoin sodium equivalents (PE).
Is phenytoin a sedative?
Chronic use of phenytoin has been shown to produce mild sedation. Because of the development of tolerance with chronic use, such level of sedation is not remarkable and thus not witnessed clinically.
Should you brush your teeth after taking phenytoin?
In some patients (usually younger patients), tenderness, swelling, or bleeding of the gums (gingival hyperplasia) may appear soon after phenytoin treatment is started. To help prevent this, brush and floss your teeth carefully and regularly and massage your gums.
Can you substitute phenytoin for Dilantin?
“If you are taking Dilantin brand, be sure to continue. If you’re getting a generic brand of phenytoin, be sure to get same-looking generics.” Meanwhile, Leppik and colleagues took their findings to the Minnesota state health authorities. They changed the rule requiring a switch to generic Dilantin.
How do you calculate corrected phenytoin level?
If clcr < 20 mL/min then Corrected Phenytoin = Total Phenytoin Level / ( (0.1 x albumin) + 0.1) This is so cool!
Can you give phenytoin IV push?
Pediatrics: A loading dose of 15-20 mg/kg of Dilantin intravenously will usually produce plasma concentrations of phenytoin within the generally accepted therapeutic range (10 20 mcg/mL). The drug should be injected slowly intravenously at a rate not exceeding 1 3 mg/kg/min or 50 mg per minute, whichever is slower.
When do you take phenytoin IV?
A level can be taken 2-4 hours following an IV loading or top-up dose (12-24 hours for oral doses) and levels should then be monitored every 24 hours until control is achieved and concentration has stabilised.
What is the composition of Epanutin?
Epanutin contains sodium benzoate, sucrose, ethanol and colouring agents sunset yellow FCF (E110) and carmoisine (E122) (see section 2). Epanutin contains 25 mg sodium benzoate in each 5 ml which is equivalent to 5 mg/ml. Benzoates may increase unconjugated bilirubin levels by displacing bilirubin from albumin, which may increase neonatal jaundice.
What is the maximum amount of Epanutin a day for adults?
another. Most adults need between 200mg and 500mg a day either as a single or divided dose. Occasionally higher doses are needed. divided dose, twice a day. The dose is then adjusted up to a maximum of 300mg a day. by their doctor. Epanutin is dangerous in overdose. If you accidentally take too hospital casualty department.
What is the best way to take Epanutin?
sure. It is best to take Epanutin at the same time each day. Swallow the capsules whole, with plenty of water. another. Most adults need between 200mg and 500mg a day either as a single or divided dose. Occasionally higher doses are needed. divided dose, twice a day. The dose is then adjusted up to a maximum of 300mg a day. by their doctor.
What medicines are high in Epanutin?
Medicines used for diabetes (tolbutamide). Medicines used for cancer (antineoplastic agents, e.g. the St John’s Wort preparation. Epanutin can be taken before or after food and drinks. You should not take Epanutin if you are breast-feeding. Epanutin contain lactose, a type of sugar.