Table of Contents
What are the lactation categories?
†— Lactation risk categories are as follows: L1 = safest; L2 = safer; L3 = moderately safe; L4 = possibly hazardous; L5 = contraindicated.
What is a Category C drug?
Category C: Studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women, or studies in women and animals are not available. Drugs from this class can be given to pregnant women if the benefit to the mother outweighs the risk to the fetus.
What is lactation medication?
There are several prescription drugs that have been used to increase milk supply: Metoclopramide (Reglan), Domperidone (Motilium), and sulpiride (Eglonyl, Dolmatil, Sulpitil, Sulparex, Equemote). The presence of an appropriate level of the hormone prolactin permits lactation to proceed normally.
Which drug is safe during lactation?
Penicillins, aminopenicillins, clavulanic acid, cephalosporins, macrolides and metronidazole at dosages at the low end of the recommended dosage range are considered appropriate for use for lactating women.
What does Category B medication mean?
Category B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
What is a L3 drug?
L3 Probably Compatible Drugs should be given only if the potential benefit justifies the potential risk to the infant. (New medications that have absolutely no published data are automatically categorized in this category, regardless of how safe they may be.)
Which drug is contraindicated in lactation?
Drugs contraindicated during breastfeeding include anticancer drugs, lithium, oral retinoids, iodine, amiodarone and gold salts. An understanding of the principles underlying the transfer into breast milk is important, as is an awareness of the potential adverse effects on the infant.
What does L2 mean in breastfeeding?
L2 – Probably Compatible Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant. And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
What is Pregnancy Category ABC?
In 1979, the FDA established five letter risk categories – A, B, C, D or X – to indicate the potential of a drug to cause birth defects if used during pregnancy. The categories were determined by assessing the reliability of documentation and the risk to benefit ratio.
What medications decrease milk supply?
Certain medications decrease milk supply, including medications containing pseudoephedrine (Sudafed, Zyrtec D, others). Your health care provider might also caution against certain types of hormonal contraception, at least until breast-feeding is firmly established. Avoid alcohol and nicotine.
How do you treat lactation failure?
Metoclopramide and chloropromazine may help certain mothers with lactation failure to revert to normal milk production through their galactagogue effect (27). Metoclopramide is a more effective releasing agent for prolactin than TRH.
What is the difference between labor and delivery and lactation?
Information formerly found in the “Labor and delivery” subsection is now included in the “Pregnancy” subsection. The Nursing mothers subsection was renamed, the Lactation subsection (8.2), and provides information about using the drug while breastfeeding, such as the amount of drug in breast milk and potential effects on the breastfed infant.
What is LactMed®?
The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant.
What drugs contain lactic acid?
Lacosamide Lactic Acid, Citric Acid, and Potassium Bitartrate Lamivudine Lamotrigine Lanadelumab Lanolin Lanreotide Lansoprazole Lanthanum Carbonate Lapatinib Laronidase Lasmiditan Latanoprost Latanoprostene Bunod Lavender Lecithin Ledipasvir Lefamulin Leflunomide Lemborexant Lemon Balm Lenvatinib Lepirudin Letermovir Letrozole Levalbuterol
Where can I find more information about medications during pregnancy?
This group maintains a website called Mother to Baby . provides up-to-date evidence-based information on the use of medications during pregnancy and breastfeeding.