Table of Contents
What is the Parafascicular nucleus?
The parafascicular nucleus (PF) of the thalamus is involved in the generation of physiological oscillatory rhythms. It receives excitatory inputs from the cortex and inhibitory inputs from the basal ganglia, a system implicated in the control of epileptic seizures.
What does the Centromedian nucleus do?
Functionally, the CM participates in sensorimotor coordination, cognition (e.g. attention, arousal), and pain processing. The role of CM as ‘gate control’ function by propagating only salient stimuli during attention-demanding tasks has been proposed.
What is function of dorsomedial nucleus of thalamus?
The medial dorsal nucleus (or dorsomedial nucleus of thalamus) is a large nucleus in the thalamus. It receives inputs from the Pre-Frontal Cortex and the Limbic System and in turn relays them to the Pre-Frontal Association Cortex.
Which thalamic nuclei receives sensory?
The medial geniculate nucleus receives auditory sensory information from the inferior colliculus and relays it to the primary auditory cortex of the temporal lobe.
What is the Centromedian nucleus of the thalamus?
The centromedian (CM) nucleus is an intralaminar thalamic nucleus that is considered as a potentially effective target of deep brain stimulation (DBS) and ablative surgeries for the treatment of multiple neurological and psychiatric disorders.
Where is the Centromedian nucleus of the thalamus?
intralaminar nuclei
The CM nucleus or centromedian–parafasicular nucleus complex, situated within the intralaminar nuclei of the thalamus, has abundant fiber connections with other thalamic nuclei, basal ganglia, and cerebral cortex (Ilyas et al., 2019).
What part of the brain receives sensory information?
Thalamus
Thalamus: The thalamus is the relay center of the brain. It receives afferent impulses from sensory receptors located throughout the body and processes the information for distribution to the appropriate cortical area.
What are association nuclei?
nuclei of the thalamus that do not receive direct input from ascending sensory systems. They connect widely with other thalamic nuclei and send axons to association cortex.
Does the thalamic parafascicular nucleus modulate basal ganglia nuclei?
During the past few years, there has been a growing body of evidence suggesting that the thalamic parafascicular nucleus in rodents (PF) exerts a multifaceted modulation of basal ganglia nuclei, at different levels.
What is the parafascicular nucleus?
We also recorded from cells in the parafascicular nucleus, a nucleus of the posterior intralaminar nuclear group, because they have unusual anatomical features that are similar to those of some of our paralaminar cells.
How can pain evoked discharges in the parafascicular nucleus be inhibited?
Pain evoked unit discharges in the parafascicular nucleus could be inhibited by direct electrical stimulation of the centromedian nucleus of thalamus, with residual inhibitory effect lasting for several minutes after cessation of stimulation.
Is parafascicular nucleus stimulation associated with indirect action through the cerebral frontal cortex?
The facilitatory effect of parafascicular nucleus stimulation does not appear to be associated with indirect action through the cerebral frontal cortex because acute lesion of the excitatory corticostriatal afferents, which by itself reduced basal ACh release by 40%, did not modify the effect of 10 Hz stimulation. The results provide in vivo evi…