Table of Contents
How does T3 help depression?
T3 may increase serotonergic neurotransmission and has been studied as an add-on agent in patients with unipolar depression with and without thyroid dysfunction to accelerate, enhance, and augment the effects of tricyclic antidepressants and selective serotonin reuptake inhibitors.
Does T3 improve mood?
In patients with unipolar depression, T3 therapy has been demonstrated to reduce the time to onset of antidepressant effects, to enhance response when used throughout the length of antidepressant therapy, and to augment the effects of antidepressants in depression that has failed to respond adequately to antidepressant …
How do I add T3 to levothyroxine?
There are several ways your physician can add T3:
- Adding synthetic T3 such as brand-name Cytomel or generic liothyronine to levothyroxine.
- Adding compounded, prescription, time-released T3 to levothyroxine.
Can cytomel help with anxiety?
Definitely helped with depression and anxiety.
Does T3 cause anxiety?
Yes, thyroid disease can affect your mood — primarily causing either anxiety or depression. Generally, the more severe the thyroid disease, the more severe the mood changes. If you have an overactive thyroid (hyperthyroidism), you may experience: Unusual nervousness.
Which is better Cytomel or Synthroid?
Although Synthroid and Cytomel are currently being used to treat hypothyroidism, there are two reasons why Synthroid might be preferred in some cases: Cytomel can be less predictable. It acts much more quickly in the body than Synthroid and can cause possible effects on the heart that can be dangerous.
How quickly does Cytomel start working?
Cytomel starts working within a few hours, but its maximum effect can take two to three days to occur. It only takes 4 hours for 95% of a dose of Cytomel to be totally absorbed.
Is anger a symptom of thyroid?
Hyperthyroidism occurs when an overactive thyroid produces too many hormones. Symptoms can include panic attacks, anxiety, tension, sleep disturbances, mood swings, a short temper, and impatience.
Does Cytomel cause hair loss?
In rare cases, temporary hair loss may occur during the first few months of starting Cytomel (especially in children).
Is there a difference between T3 and T4 augmentation in depressed patients?
Conclusion: These results are consistent with a report of differential effects for T3 versus T4 augmentation in depressed patients free of thyroid disease. The results have implications for the treatment of depression in the presence of thyroid disease and for the mechanism of thyroid hormone potentiation of antidepressants.
Is T3 augmentation safe and effective for euthyroid patients with unipolar depression?
Despite these limitations, T3 augmentation appears to be a safe and effective alternative treatment for euthyroid patients with unipolar depression who receive appropriate baseline and follow-up safety monitoring. Footnotes FUNDING:No funding was received for the preparation of this article.
Does triiodothyronine augmentation improve treatment-resistant major depressive disorder?
An open study of triiodothyronine augmentation of selective serotonin reuptake inhibitors in treatment-resistant major depressive disorder. J Clin Psychiatry.
Can liothyronine sodium (levorotary isomer of triiodomethronine [T3] be used for antidepressant augmentation?
Background: Clinicians may not consider using the thyroid hormone liothyronine sodium (levorotary isomer of triiodothyronine [T3]) for augmentation of antidepressant drugs in depressed patients who are also receiving the precursor hormone levothyroxine (levorotary isomer of thyroxine [T4]) for thyroid disease.