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How do you administer SIMPONI injection?
For RA, PsA, and AS: SIMPONI® 50 mg is given as an injection under the skin (subcutaneous injection) once a month. For UC: SIMPONI® begins with 3 starter injections under the skin (subcutaneous injection): Two 100-mg injections on the first day of treatment, followed by one 100-mg injection 2 weeks later.
How is golimumab administered?
The SIMPONI dose regimen is 50 mg administered by subcutaneous injection once a month.
How is Simponi Aria administered?
It is administered to you as an intravenous(IV) infusion to reduce signs and symptoms of moderate to severe rheumatoid arthritis (RA), such as joint swelling, pain, fatigue, and length of morning stiffness. Golimumab is commonly known as Simponi Aria®. It can also be given as an injection.
What’s the difference between SIMPONI and Simponi aria?
Simponi and Simponi Aria for psoriatic arthritis “Active” means the condition currently causes symptoms. Simponi is approved for use in adults alone or in combination with methotrexate. Simponi Aria is approved to treat PsA in adults as well. But the medication can also be used in children ages 2 years and older.
How do you give an injection without pain?
There are some tips that can make giving an injection less painful:
- Allow the medicine to come to room temperature (but do not heat it).
- Always use a new needle. Used ones are not only unsterile but can be blunt.
- Position the needle at 90 degrees to the injection site.
- Stick the needle in quickly.
How do you inject biologics?
The most common places to self-inject biologics are in the thigh or the abdomen, Dr. Troum says. Technically you can do it in the same place every time, but injection sites often develop sensitivity or pain over time. Over years you may even build up scar tissue.
How do you reconstitute Simponi Aria?
Dilute the total volume of the SIMPONI ARIA solution with 0.9% Sodium Chloride Injection, USP to a final volume of 100 mL. For example, this can be accomplished by withdrawing a volume of the 0.9% Sodium Chloride Injection, USP from the 100-mL infusion bag or bottle equal to the total volume of SIMPONI ARIA.
What is the difference between Remicade and Simponi Aria?
Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects. Calms down the immune system. Simponi (golimumab) effectively calms down your immune system, but it is given as a shot and puts you at risk of serious infections like tuberculosis or hepatitis B.
How deep should intramuscular injection needles be?
A 1–1½” needle is recommended in women weighing 152–200 lbs (70–90 kg) and men weighing 152–260 lbs (70–118 kg). A 1½” needle is recommended in women weighing more than 200 lbs (90 kg) or men weighing more than 260 lbs (118 kg). Use a needle long enough to reach deep into the muscle.
How many mg are in a vial of SIMPONI ARIA?
Each single-use 4-mL vial of SIMPONI ARIA® contains 50 mg of golimumab. You may refer to the SIMPONI ARIA® dosing calculator to calculate the recommended dosage of SIMPONI ARIA® based on patient weight.
Does Simponi have a black box warning?
Simponi carries a black box warning from the U.S. Food and Drug Administration (FDA), which is the most serious warning issued by the agency. It alerts healthcare providers and patients to potentially serious side effects that can lead to injury and death.
Can Simponi cause hair loss?
Hair loss isn’t a side effect of Simponi or Simponi Aria. Hair loss wasn’t a side effect reported for either drug in studies. However, methotrexate, which may be prescribed with Simponi or Simponi Aria, can cause hair loss. If you’re experiencing hair loss that bothers you, talk with your doctor or pharmacist.
Can I take methotrexate and SIMPONI on the same day?
When treating RA, SIMPONI® is taken with another medicine called methotrexate, as directed. Studies have found that when methotrexate is taken with some biologic treatments, like SIMPONI®, the 2 medicines together may help to control the symptoms of RA.