Table of Contents
Is chlorothalonil toxic to humans?
Chlorothalonil is in acute Toxicity Category IV (the least toxic of four categories) for the oral route of exposure, and in Toxicity Category II for the inhalation route. For acute dermal effects and acute skin irritation, chlorothalonil is in Toxicity Category IV.
What group fungicide is chlorothalonil?
Chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile) is an organic compound mainly used as a broad spectrum, nonsystemic fungicide, with other uses as a wood protectant, pesticide, acaricide, and to control mold, mildew, bacteria, algae.
Is chlorothalonil banned in Canada?
Under the authority of the Pest Control Products Act, the PMRA has determined that continued registration of products containing chlorothalonil is acceptable.
Is chlorothalonil an organochlorine pesticide?
Chlorothalonil is a broad spectrum, non systemic, organochlorine pesticide that was first registered in 1966 for turf grasses, and later for several food crops.
Is chlorothalonil a systemic fungicide?
Chlorothalonil is the third highest production volume fungicide after sulfur and copper formulations. It is a broad spectrum, non-systemic fungicide used very widely on peanuts and potatoes, as well as in many other applications.
Is chlorothalonil a contact fungicide?
A professional broad-spectrum contact fungicide that controls more than 50 major diseases on turf and ornamental plants.
Is chlorothalonil banned in UK?
The maximum use-by date for the UK and other EU member states is Wednesday 20 May 2020, after which it will be illegal to store and use CTL.
Is chlorothalonil carcinogenic?
It is used as a fungicide for plants and crops. * Chlorothalonil is on the Hazardous Substance List because it is cited by DOT, DEP, IARC, IRIS and EPA. * This chemical is on the Special Health Hazard Substance List because it is a CARCINOGEN.
Is chlorothalonil safe for bees?
Chlorothalonil is a broad-spectrum agricultural fungicide that is often applied to crops in bloom when honeybees are present for pollination because it is currently deemed safe to bees. Chlorpyrifos is a widely used organophosphate in crop management.
What is the common name for chlorothalonil?
Some popular trade names for chlorothalonil include Bravo, Daconil 2787, Echo, Exotherm Termil, Nopcocide, Repulse, and Tuffcide. This compound can be found in formulations with many other pesticide compounds.
What is the mode of action of chlorothalonil?
The general mechanism of action of chlorothalonil resembles the trichloromethyl sulfenyl fungicides in that treated cells accumulate large concentrations of fungicide; reactions involve both low and high molecular-weight thiols, with the formation of glutathione-fungicide derivatives; and toxicity resides ultimately …
What is a group 4 fungicide?
The phenylamide fungicides (FRAC group 4) are a highly active class of fungicides that target oomycete pathogens such Phytophthora and Pythium spp.
Is chlorothalonil toxic if inhaled?
According to the United States Environmental Protection Agency, chlorothalonil is a toxicity category I eye irritant, producing severe eye irritation. It is in toxicity category II, “moderately toxic”, if inhaled (inhaled LD50 0.094 mg/l in rats.) For skin contact and ingestion, chlorothalonil is rated toxicity category IV,…
What are the side effects of chlorothalonil in rabbits?
Chlorothalonil causes irreversible and severe ocular lesion in rabbits. Signs of toxicity include decreased body weight and decreased hematological parameters, increased absolute kidney weight, vacuolar degeneration in the proximal tubular epithelium and hyperplasia of forestomach. Chlorothalonil is not genotoxic in vivo.
What are the routes of exposure to chlorothalonil?
The primary routes of exposure to chlorothalonil are ingestion, inhalation, dermal, and ocular. Occupational exposure to chlorothalonil may occur through inhalation of dusts or dermal contact with this compound at workplaces where it is produced or used as a pesticide.
How does chlorothalonil deactivate glutathione?
Chlorothalonil reduces and thereby deactivates glutathione. Its mechanism of action is similar to that of trichloromethyl sulfenyl fungicides such as captan and folpet. According to the EPS, chlorothalonil is a toxicity category I eye irritant, producing severe eye irritation.