Table of Contents
What is Clivus chordoma?
Clivus chordoma Arising from the embryonic rests of the notochord al, clivus chordoma are slow-growing yet aggressively invasive and destructive tumor s.
What is the prognosis of clival chordoma due to seeding?
Recurrence of clival chordoma due to seeding along the surgical pathway is an infrequent mechanism of treatment failure, with only rare cases documented in the literature. When deciding on the appropriate surgical approach, the surgeon must consider the risk of septal seeding during a transseptal approach.
What is a chordoma?
Chordomas are uncommon malignant tumors of the axial skeleton that account for 1% of intracranial tumors and 4% of all primary bone tumors. They originate from embryonic remnants of the primitive notochord (earliest fetal axial skeleton, extend… Articles Log In Cases Sign Up Courses Quiz Donate About Menu Search
What is a clival region tumor?
The clival region is the second most common location, accounting for 30-35% of cases 2,3. Typically the mass projects posteriorly at midline, indenting the pons; this characteristic appearance has been termed the so-called thumb sign. In contrast to sacrococcygeal tumors, there is no recognized gender difference. Vertebral bodies
What is chordoma?
In layman’s terms, chordoma is a type of spinal cancer. Chordomas can arise from bone in the skull base and anywhere along the spine. The two most common locations are cranially at the clivus and in the sacrum at the bottom of the spine. MRI of extensive clival chordoma in 17-year-old male patient, sagittal view.
What is the prognosis of notochord al Clivus chordoma?
Arising from the embryonic rests of the notochord al, clivus chordoma are slow-growing yet aggressively invasive and destructive tumor s. Poorly differentiated chordoma with SMARCB1 /INI1 loss: a distinct molecular entity with dismal prognosis 1).
What is the pathophysiology of chordoma of the notochord?
Chordoma is a rare slow-growing neoplasm thought to arise from cellular remnants of the notochord. The evidence for this is the location of the tumors (along the neuraxis ), the similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the clivus…