Table of Contents
What is Gamna-Gandy bodies spleen?
Gamna-Gandy bodies (siderotic nodules) represent organized foci of hemorrhage in the spleen that is caused by portal hypertension. Gamna-Gandy bodies contain hemosiderin, fibrous tissue, and calcium.
What is the composition of Gamna-Gandy bodies?
Gamna-Gandy bodies (GGBs), also called tobacco flecks or siderotic nodules, appear as yellow-brownish and spheroidal foci within the splenic parenchyma, are composed of deposits of iron pigments and calcium salts, and are associated with granulomatous inflammatory reactions with multinucleated foreign-body giant cells …
What is splenic Siderosis?
Splenic siderotic nodules, also known as Gamna-Gandy bodies, of the spleen, are most commonly encountered in portal hypertension. The pathophysiological process is the result of microhemorrhage resulting in hemosiderin and calcium deposition followed by fibroblastic reaction.
What is a granuloma in the spleen?
Splenic granulomatous disease refers to sequelae arising from granulomatous infection-inflammation of the spleen. They are a result of: infective. splenic tuberculosis. splenic histoplasmosis.
What is Banti’s disease?
Banti syndrome is a disorder of the spleen, the large, gland-like organ in the upper left side of the abdomen that produces red blood cells before birth and, in newborns, removes and destroys aged red blood cells, and plays a role in fighting infection.
What will an MRI of the spleen show?
Nowadays, MRI permits the characterization of the most common splenic lesions, such as cysts, small hemangiomas, and hamartomas, and improvement in the detection of malignant diseases such as lymphoma and metastases [1].
What type of tissue is found in the spleen?
Surrounded by a connective tissue capsule, which extends inward to divide the organ into lobules, the spleen consists of two types of tissue called white pulp and red pulp.
How long does a spleen MRI take?
The technologist will have you lie onto the imaging table and a five minute image will be taken over your abdomen area to include the liver and spleen. There will be an additional set of images taken called a SPECT/CT and this takes approximately 20 minutes.
Can MR imaging detect Gamna-Gandy nodules in portal hypertension?
Gamna-Gandy bodies of the spleen: evaluation with MR imaging The authors retrospectively evaluated magnetic resonance (MR) images obtained in 64 patients with portal hypertension. Multiple low-intensity nodules were noted within the spleen in eight patients.
What are Gamna Gandy foci on CT?
Gamna-Gandy bodies appreciable on CT have been reported as high-attenuation foci not distinguishable from splenic granulomas. They are rarely well demonstrated by CT 2. Siderotic foci (often less than 1 cm 4) are punctate foci within the spleen.
Do low-intensity nodules seen on MR images represent hemosiderin deposits of Gamna-Gandy bodies?
Although there was no pathologic proof in their series, the authors believe these low-intensity nodules seen on MR images may represent the hemosiderin deposits of Gamna-Gandy bodies. Publication types Comparative Study MeSH terms Adult