Is mesenchymal stem cell therapy safe?
Safety of Mesenchymal Stem Cell Therapies After a thorough analysis of 36 studies, they found that there was no relationship between the use of MSCs and tumorigenic potential, and no serious side effects of the therapy were reported89. The safety and impact of MSCs therapy were also investigated by Karussis et al.
Is mesenchymal stem cell therapy FDA approved?
Currently, there is no Food and Drug Administration (FDA)-approved MSC therapy on the market in the United States although several MSC products have been granted regulatory approval in other countries.
What can mesenchymal stem cells treat?
The therapeutic benefits of MSCs have prompt their use in cell-based strategies to treat different diseases, including cancer. Similar to damaged tissues, tumors exert chemoattractant effects on MSCs that influence their recruitment to tumor sites (Figure 2).
How long do mesenchymal stem cells last in the body?
MSC are short-lived after administration. In vitro expanded MSC have a short lifetime after in vivo administration. Intravenously infused MSC home to the lungs, from where they disappear within 24h. Living MSC are not detected at other tissue sites.
What are the downsides of stem cell therapy?
Other side effects are related to the stem cell transplant.
- Low blood cell counts. You will have low blood cells counts after a stem cell transplant.
- Infection.
- Bleeding.
- Anemia.
- Graft-versus-host disease (GVHD)
- Veno-occlusive disease (VOD)
- Digestive system problems.
- Skin and hair problems.
What are mesenchymal stem cells made of?
Mesenchymal stem cells are adult stem cells isolated from different sources that can differentiate into other types of cells. In humans, these sources include; bone marrow, fat (adipose tissue), umbilical cord tissue (Wharton’s Jelly) or amniotic fluid (the fluid surrounding a fetus).