What is HPV PPT?
1. Human papilloma virus Human papillomavirus is the most common sexually transmitted infection. Most sexually active men and women being exposed to the virus at some point during their lifetime.
What is human papillomavirus PDF?
Human papillomavirus (HPV) belonging to Papillomaviridae (family of Papillomavirus). HPV infection causes various types of disorders and diseases including cervical, vaginal, anal, penile, oropharyngeal, and lung cancer also cancer in head and neck along with some malignant and benign warts.
What are the types of HPV?
There are about 14 high-risk HPV types including HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. Two of these, HPV16 and HPV18, are responsible for most HPV-related cancers.
What is the pathogenesis of human papillomavirus infection?
The productive life cycle of HPVs is linked to epithelial differentiation. Papillomaviruses are thought to infect cells in the basal layer of stratified epithelia and establish their genomes as multicopy nuclear episomes. In these cells, viral DNA is replicated along with cellular chromosomes.
What is the pathophysiology of HPV?
Clinical manifestations of HPV infection include anogenital warts, recurrent respiratory papillomatosis, cervical cancer precursors (cervical intraepithelial neoplasia), and cancers, including cervical, anal, vaginal, vulvar, penile, and oropharyngeal cancer. HPV is not cultured by conventional methods.
What is human papillomavirus Pubmed?
The human papillomavirus (HPV) is a non-enveloped, double-stranded, circular DNA virus that is responsible for causing multiple epithelial lesions and cancers. It can manifest as cutaneous and anogenital warts, which depending on the subtype, may progress to carcinoma.
Where is human papillomavirus found?
HPV lives in thin, flat cells called epithelial cells. These are found on the skin’s surface. They’re also found on the surface of the vagina, anus, vulva, cervix and head of the penis. They’re also found inside the mouth and throat.
What is human papillomavirus Wikipedia?
Human papillomavirus infection (HPV infection) is caused by a DNA virus from the Papillomaviridae family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions.
What causes HPV virus?
HPV causes The virus that causes HPV infection is transmitted through skin-to-skin contact. Most people get a genital HPV infection through direct sexual contact, including vaginal, anal, and oral sex. Because HPV is a skin-to-skin infection, intercourse isn’t required for transmission to occur.
How do you diagnose human papillomavirus?
Your doctor collects a sample of cells from your cervix or vagina to send for laboratory analysis. Pap tests can reveal abnormalities that can lead to cancer. DNA test. This test, conducted on cells from your cervix, can recognize the DNA of the high-risk varieties of HPV that have been linked to genital cancers.
What are the virulence factors of human papillomavirus?
The virulence of HPV is mainly exhibited by E5, E6 and E7 encoded oncoproteins that cause low to high-grade cervical lesions (CIN-1, 2, 3), leading to form 99.7% of squamous cell and 89% of adenocarcinomas cervical cancer worldwide.
What type of pathogen causes papillomas?
human papillomavirus (HPV), any of a subgroup of viruses belonging to the family Papovaviridae that infect humans, causing warts (papillomas) and other benign tumours as well as cancers of the genital tract, especially of the uterine cervix in women.
What are the 3 strains of HPV?
High-risk HPV strains include HPV 16 and 18, which cause about 70% of cervical cancers. Other high-risk human papillomaviruses include 31, 33, 45, 52, 58, and a few others. Low-risk HPV strains, such as HPV 6 and 11, cause about 90% of genital warts, which rarely develop into cancer.
What causes human papillomavirus?
How is HPV diagnosed?
Is human papillomavirus a virus or bacteria?
HPV, or human papillomavirus, is a common virus that can cause cancers later in life. You can protect your child from these cancers with HPV vaccine at age 11–12 years.
What is the pathophysiology of human papillomavirus?
Human papillomaviruses (HPVs) are small, double-stranded DNA viruses that infect cutaneous and mucosal epithelial tissues of the anogenital tract, the hands, or the feet. A subset of HPV types are the causative agents of cervical cancer, since 99% of tumors are positive for HPV DNA (150).
What cells do papilloma viruses infect?
The consensus is that the virus infects the basal epithelial cells through microlesions and replicates to a stable level of 50–100 copies per cell in the basal layer.