Table of Contents
What is endoscopic Ampullectomy?
Endoscopic ampullectomy is a minimally invasive method of treating superficial lesions of the ampulla of Vater. With careful patient selection and lesion assessment it is a safe and efficacious therapeutic procedure that can obviate the need for potentially major surgical intervention.
Where is the ampulla of Vater?
The ampulla of Vater is a small opening that enters into the first portion of the small intestine, known as the duodenum. The ampulla of Vater is the spot where the pancreatic and bile ducts release their secretions into the intestines.
What is ampulla biopsy?
Biopsy of the ampulla of Vater may be performed to evaluate for ampullary adenomas, suspected ampullary tumors and immunohistological staining for autoimmune pancreatitis. Ampullary biopsies are commonly performed at the time of endoscopic retrograde cholangiopancreatography (ERCP).
What is a Ampullectomy?
An ampullectomy is a surgical procedure that is used to treat cancers of the hepatopancreatic duct (ampullary adenomas), small neuroendocrine tumors that develop in the ampulla of Vater and certain noncancerous conditions, such as inflammatory stenosis.
What is the function of ampulla of Vater?
The papilla of Vater is involved in the regulation of bile flow (inhibition and facilitation) into the duodenum and the prevention of reflux into the bile and pancreatic duct system. These functions are achieved by a special muscular, neural and mucosal structure of the papilla of Vater.
What is ampullary Vater?
The ampulla of Vater is located where your bile duct and pancreatic duct join and empty into your small intestine. Ampullary (AM-poo-la-ree) cancer is a rare cancer that forms in an area of your digestive system called the ampulla of Vater.
How is Ampullectomy performed?
The surgeon carefully identifies the pancreatic and bile ducts. Superficial cancerous cells on the ampulla are surgically removed (excised) with the help of needle-tip electrocautery. Both the pancreatic and bile ducts are marked with stitches before completing the excision.
What is the difference between endoscopy and ERCP?
They are relatively similar to each other as both involve the use of an endoscope. The main difference between the two is that endoscopic ultrasound utilizes high-frequency sound waves to generate a virtual image and ERCP procedure uses a video camera.
Can ampullary tumors be benign?
Benign neoplasms of the ampulla of Vater are rare, representing less than 10 percent of periampullary neoplasms [1,2]. Adenomas are the most common benign lesions of the ampulla but have the potential to undergo malignant transformation to ampullary carcinomas [1,3-19].
Is ampulla of Vater same as major duodenal papilla?
The major duodenal papilla (papilla of Vater) is the point where the dilated junction of the bile and pancreatic ducts (ampulla of Vater) enter the duodenum.
What’s an ERCP procedure?
Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that combines upper gastrointestinal (GI) endoscopy and x-rays to treat problems of the bile and pancreatic ducts.
What is the function of the ampulla of Vater?
The ampulla of Vater is a small opening that enters into the first portion of the small intestine, known as the duodenum. The ampulla of Vater is the spot where the pancreatic and bile ducts release their secretions into the intestines. Facts about ampullary cancer Ampullary cancer is a fairly rare form of cancer.
What are the neoplasms of the ampulla of Vater?
The ampulla of Vater can exhibit a variety of neoplasms, such as carcinoma, adenoma, neuroendocrine tumor, gangliocytic paraganglioma and gastrointestinal stromal tumor (GIST). GISTs are mesenchymal tumors of the gastrointestinal tract that express the tyrosine kinase receptor and originate from the interstitial cells of Cajal.
How common are gastrointestinal stromal tumors of the ampulla of Vater?
Gastrointestinal stromal tumors (GISTs) usually develop in the stomach and small intestine and only rarely occur at the ampulla of Vater, with only 11 cases reported in the literature. We report a case of a GIST of the ampulla of Vater. A 36-year-old, previously healthy man presented with a loss of consciousness lasting a few minutes.
Does cap-assisted endoscopy increase ampulla of Vater visualization in high-risk patients?
Cap-assisted endoscopy increases ampulla of Vater visualization in high-risk patients ClinicalTrials.gov , NCT02867826 , 16 August 2016. ClinicalTrials.gov , NCT02867826 , 16 August 2016.