Table of Contents
What is Streptococcus pneumoniae IgG?
Streptococcus pneumoniae is a gram-positive bacteria that causes a variety of infectious diseases in children and adults. More than 90 serotypes of Streptococcus pneumoniae have been identified, based on cell wall polysaccharides.
What does high pneumococcal titers mean?
Pneumococcal titer levels ≥0.2 µg/mL were considered as protective against invasive pneumococcal disease, and levels ≥1.3 µg/mL were considered protective against noninvasive pneumococcal disease.
What does it mean if your pneumococcal antibodies are low?
When total immunoglobulins or IgG subclasses are low, a more profound immunodeficiency is usually present. Some patients have low antibody titers to Streptococcus pneumoniae during the initial evaluation, and this finding usually requires vaccination and additional testing.
What Antibiotics treat pneumonia?
The first-line treatment for pneumonia in adults is macrolide antibiotics, like azithromycin or erythromycin. In children, the first-line treatment for bacterial pneumonia is typically amoxicillin.
Is IgG deficiency serious?
People with IgG deficiency are more likely to get infections. When your body feels it is under attack, it makes special proteins called immunoglobulins or antibodies. These antibodies are made by the plasma cells. They are let loose throughout the body to help kill bacteria, viruses, and other germs.
Can pneumococcal pneumonia be cured?
Doctors use antibiotics to treat pneumococcal disease. However, some pneumococcal bacteria have become resistant to certain antibiotics used to treat these infections. Available data show that pneumococcal bacteria are resistant to one or more antibiotics in 3 out of every 10 cases.
What is Streptococcus pneumoniae?
Streptococcus pneumoniae. Streptococcus pneumoniae (S. pneumoniae) are lancet-shaped, gram-positive, facultative anaerobic bacteria with over 90 known serotypes. Most S. pneumoniae serotypes can cause disease, but only a minority of serotypes produce the majority of pneumococcal infections. Pneumococci are common inhabitants…
What is the humoral immune response to Streptococcus pneumoniae?
The humoral immune response to S. pneumoniae is age dependent, and the database of IgG antibody concentrations to different serotypes is incomplete. The minimum concentration of IgG antibody necessary to ensure protection against invasive disease has not been determined for any serotype.
How many known serotypes of Streptococcus pneumoniae are there?
There are 100 known serotypes of Streptococcus pneumoniae, the bacteria that cause pneumococcal disease. Streptococcus pneumoniae are lancet-shaped, gram-positive, facultative anaerobic bacteria with 100 known serotypes.
What is an IgG antibody assessment?
Assessing the IgG antibody response to active immunization with conjugated, 13-valent vaccines. Determining the ability of an individual to produce an antibody response to polysaccharide antigen (s), as part of an evaluation for humoral or combined immunodeficiencies.