Table of Contents
How does Illumina genotyping work?
How Do Illumina Microarrays Work? As DNA fragments pass over the BeadChip, each probe binds to a complementary sequence in the sample DNA, stopping one base before the locus of interest. Allele specificity is conferred by a single base extension that incorporates one of four labeled nucleotides.
What can genotyping tell you?
Genotyping determines differences in genetic complement by comparing a DNA sequence to that of another sample or a reference sequence. It identifies small variations in genetic sequence within populations, such as single-nucleotide polymorphisms (SNPs).
What is the difference between genotyping and sequencing?
Genotyping is like reading a few scattered words on a page. Sequencing reads whole sentences, paragraphs and chapters. To sum it up quickly, genotyping gives you small packets of data to compare while sequencing gives you more data, with more meaning and context, today and down the road.
What is included in the genomestudio software guide?
Instructions for the GenomeStudio GT Module, GenomeStudio Methylation Module, GenomeStudio Gene Expression Module, and GenomeStudio Polyploid Clustering Module. Software guide for the BeadArray Controls Reporter, including an analysis overview, output file descriptions, sample sheet specifications, and troubleshooting.
What is the genomestudio framework?
As in all GenomeStudio modules, the GenomeStudio Framework displays data output in tabular form and enables you to visualize your results quickly and easily using the Illumina Genome Viewer and Illumina Chromosome Browser graphical tools.
What is the genomestudio genotyping (GT) module?
The GenomeStudio Genotyping (GT) Module supports the analysis of Infinium and GoldenGate genotyping array data. This module enables efficient genotyping data normalization, genotype calling, clustering, data intensity analysis, loss of heterozygosity (LOH) calculation, and copy number variation (CNV) analysis.
How much does genomestudio cost?
Access to GenomeStudio 2.0 is now free. Start using GenomeStudio 2.0. Interested in receiving newsletters, case studies, and information on genomic analysis techniques? Enter your email address.