What is imidazole used for?
A topical antifungal used to treat a variety of dermatophyte infections. An imidazole antifungal used to treat vulvovaginal candidiasis. A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Is imidazole an antifungal?
Imidazoles are one of the most promising and vigorously pursued areas of contemporary antifungal chemotherapy depicting broad spectrum and potent activity.
Is imidazole an antibiotic?
Imidazole Antibiotics Inhibit the Nitric Oxide Dioxygenase Function of Microbial Flavohemoglobin – PMC. The . gov means it’s official.
Is fluconazole an imidazole?
Itraconazole and fluconazole are the most active of the antifungal imidazoles. Their spectrum includes dimorphic fungal organisms and dermatophytes. They are also effective against some cases of aspergillosis (60%–70%) and cutaneous sporotrichosis.
What are the side effects of imidazole?
The imidazoles given PO result in few adverse effects, but nausea, vomiting, and hepatic dysfunction can develop. Ketoconazole in particular is associated with hepatotoxicity, especially in cats.
Is clotrimazole an imidazole?
Clotrimazole, an imidazole antimycotic, interferes with the rise in cytosolic Ca2+ and inhibits cell proliferation in a reversible manner. Here we describe the effect of clotrimazole on vascular endothelial cells (ECs).
Does fluconazole cause liver damage?
Fluconazole is a triazole fungistatic agent used in the treatment of systemic and superficial fungal infections. Fluconazole therapy can cause transient mild-to-moderate serum aminotransferase elevations and is a known cause of clinically apparent acute drug induced liver injury.
Is imidazole a drug?
Drug type: Dacarbazine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
What is clotrimazole used for?
About clotrimazole It’s used to treat skin infections caused by a fungus (yeast). Clotrimazole treats different types of fungal infections including: athlete’s foot. ringworm.