Table of Contents
What is the drug pantoprazole used for?
It’s used for heartburn, acid reflux and gastro-oesophageal reflux disease (GORD) – GORD is when you keep getting acid reflux. It’s also taken to prevent and treat stomach ulcers. Sometimes, pantoprazole is taken for a rare condition caused by a tumour in the pancreas or gut called Zollinger-Ellison syndrome.
Can pantoprazole and sucralfate be taken together?
If you are also taking sucralfate, take pantoprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better.
What is pantoprazole a MOA?
The mechanism of action of pantoprazole is to inhibit the final step in gastric acid production. In the gastric parietal cell of the stomach, pantoprazole covalently binds to the H+/K+ ATP pump to inhibit gastric acid and basal acid secretion. The covalent binding prevents acid secretion for up to 24 hours and longer.
Does pantoprazole cause diarrhea?
The more common side effects that can occur with pantoprazole include: headache. diarrhea. stomach pain.
How good is pantoprazole?
98.4% of patients receiving pantoprazole for 4 weeks experienced significant relief of leading symptoms with the average score of 1.11. 93.6% of patients reported average leading symptom severity score of 0.54 after 8 weeks of treatment.
What class of drug is pantoprazole?
Pantoprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.
What is the contra indication of pantoprazole?
Pantoprazole is contraindicated in patients with a history of hypersensitivity to the drug itself, components of the formulation, and/or other benzimidazole PPIs, including omeprazole, lansoprazole, rabeprazole, esomeprazole, or dexlansoprazole.
Which is safer omeprazole or pantoprazole?
Omeprazole and pantoprazole are considered safe and equally effective. Both fall into a class of drugs called proton pump inhibitors (PPIs), which work by blocking acid production in the stomach (Strand, 2017).
Is pantoprazole stronger than omeprazole?
Does Pantoprazole Work Better Than Omeprazole? Generally, pantoprazole and omeprazole are equally effective. Studies comparing pantoprazole and omeprazole have found pantoprazole as effective as omeprazole in treating GERD as well as treating stomach ulcers.