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Which of the following is a serious side effect to monitor for a patient receiving erlotinib?
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.
Which type of cancer is erlotinib most often prescribed to treat?
Erlotinib is used to treat certain types of non-small cell lung cancer that has spread to nearby tissues or to other parts of the body in patients who have already been treated with at least one other chemotherapy medication and have not gotten better.
What does erlotinib Tarceva do?
Erlotinib is a type of targeted cancer drug, and is also known by its brand name Tarceva (pronounced tar-see-vah). It is a treatment for: non small cell lung cancer (NSCLC) that has spread (advanced) advanced pancreatic cancer – alongside the chemotherapy drug gemcitabine.
Can Tarceva cause eye problems?
Diarrhea, dry skin, muscle/joint pain, mouth sores, unusual eyelash growth, or eye dryness/redness/irritation may occur.
Does Tarceva cure lung cancer?
Randomized, controlled clinical studies have demonstrated that erlotinib significantly improved survival in patients with previously treated non–small-cell lung cancer and, in combination with chemotherapy, in patients with untreated pancreatic cancer.
Is Tarceva a chemotherapy?
Note: Tarceva is not a chemotherapy drug. It’s considered to be a targeted therapy.
Does Tarceva make you tired?
The most common adverse reactions in pancreatic cancer patients receiving TARCEVA 100 mg plus gemcitabine were fatigue, rash, nausea, anorexia and diarrhea. In the TARCEVA plus gemcitabine arm, Grade 3-4 rash and diarrhea were each reported in 5% of patients.
Does erlotinib cause hair loss?
In the present cases, patients experienced hair loss and a reduced growth rate, and commonly curly and brittle hair. However, in case 4, the patient’s hair became curly but rigid (Fig.
How effective is Tarceva in lung cancer?
Disease stabilization was achieved in 35% of patients treated with Tarceva™ and progression of cancer occurred in 38% of patients treated with Tarceva™. Conversely, 57% of patients who received placebo had disease progression.
How effective is Tarceva?
The overall anti-cancer response rate was 9% for patients treated with Tarceva™ and the average duration of response was nearly 8 months. Disease stabilization was achieved in 35% of patients treated with Tarceva™ and progression of cancer occurred in 38% of patients treated with Tarceva™.
What are the side effects of erlotinib (Tarceva)?
Note: This document contains side effect information about erlotinib. Some of the dosage forms listed on this page may not apply to the brand name Tarceva. Common side effects of Tarceva include: infection, conjunctivitis, diarrhea, dyspnea, keratoconjunctivitis, nausea, pruritus, skin rash, stomatitis, anorexia, and xeroderma.
What are the side effects of Tarceva eye drops?
In Summary. Common side effects of Tarceva include: infection, conjunctivitis, diarrhea, dyspnea, keratoconjunctivitis, nausea, pruritus, skin rash, stomatitis, anorexia, and xeroderma.
How does erlotinib interact with other medications or foods?
Grapefruit and grapefruit juice may interact with erlotinib and lead to unwanted side effects. Avoid the use of grapefruit products while taking Tarceva. Avoid taking an herbal supplement containing St. John’s wort at the same time you are taking Tarceva. Erlotinib can pass into body fluids (including urine, feces, vomit).
What is the solubility of Erlotinib hydrochloride?
Aqueous solubility of erlotinib hydrochloride is dependent on pH with increased solubility at a pH of less than 5 due to protonation of the secondary amine. Over the pH range of 1.4 to 9.6, maximal solubility of approximately 0.4 mg/mL occurs at a pH of approximately 2.