Table of Contents
How is Bronchorrhea treated?
What are the options for treatment?
- antibiotics, such as clarithromycin (Biaxin)
- steroids, such as inhaled beclomethasone (QVAR)
- an inhaled nonsteroidal anti-inflammatory drug (NSAID), such as indomethacin.
- the man-made hormone octreotide.
- EGFR-targeted medicines, such as gefitinib (Iressa) and erlotinib (Tarceva)
What causes Bronchorrhea?
Bronchorrhea is the production of more than 100 mL per day of watery sputum. Chronic bronchitis is a common cause, but it may also be caused by asthma, pulmonary contusion, bronchiectasis, tuberculosis, cancer, scorpion stings, severe hypothermia and poisoning by organophosphates and other poisons.
How do you sleep with fluid in your lungs?
You might find it more comfortable to sit on the edge of the bed or in an armchair. Lean forward with your arms resting on a pillow on a bed table to allow your lungs to expand as fully as possible. Let your doctor or nurse know if you find it difficult to cope. They can prescribe medicines to help you.
Can fluid in lungs drain on its own?
As long as the drainage bottle or bag is kept lower than your chest, the fluid drains out automatically. If there is a lot of fluid, this can take several hours. It has to be done slowly, because draining a large amount of fluid too quickly can make your blood pressure drop suddenly making you feel faint.
What causes fluid build up around the lungs?
Pleural effusion occurs when fluid builds up in the space between the lung and the chest wall. This can happen for many different reasons, including pneumonia or complications from heart, liver, or kidney disease. Another reason could be as a side effect from cancer.
Can diuretics remove fluid from lungs?
Depending on the severity of the condition and the reason for the pulmonary edema, treatment might include one or more of the following medications: Diuretics. Diuretics, such as furosemide (Lasix), decrease the pressure caused by excess fluid in the heart and lungs. Blood pressure drugs.
Does Lasix help pulmonary edema?
Diuretics, such as furosemide (Lasix), decrease the pressure caused by excess fluid in the heart and lungs. Blood pressure drugs. These help manage high or low blood pressure, which can occur with pulmonary edema. A provider may also prescribe medications that lower the pressure going into or out of the heart.
Does Lasix remove fluid from lung?
For the first time, this explains why Lasix, a commonly prescribed drug, works in treating lung edema — it simply prevents the pumps from allowing fluid into the air spaces. Lasix was previously believed to work exclusively by targeting the kidneys.
Which diuretic is preferred in cardiac edema?
Furosemide is by far the most common oral loop diuretic, but patients with resistance to oral furosemide therapy may benefit from trials with second-generation oral loop diuretics (bumetanide and torasemide). These may be more efficacious, due to their increased oral bioavailability and potency.
Is octreotide effective for the treatment of bronchioloalveolar cell carcinoma?
Octreotide also has been successfully used for the management of bronchorrhea in both inpatient and outpatient settings. We report the case of a 47-year-old female with a history of bronchioloalveolar cell carcinoma whose copious bronchial secretions were controlled with octreotide.
What is Oct octreotide used for?
Octreotide, a synthetic analogue of the hormone somatostatin, is primarily used in palliative medicine because of its antisecretory effect and has been shown to be effective in the management of bowel obstruction, nausea, and diarrhea.
Which medications are used in the treatment of bronchorrhea?
Inhaled indomethacin was reported to be effective for severe refractory bronchorrhea in two patients with BAC, not only reducing sputum volume but also improving quality of life.10 There also have been promising reports of the use of gefitinib in the management of bronchorrhea. Gefitnib is an oral selective EGFR-tyrosine kinase inhibitor.
Is gefitinib effective in the treatment of bronchorrhea?
The authors suggest that successful use of gefitinib for bronchorrhea is independent of its antiproliferative effect and likely secondary to the role of EGFR in regulating mucin production.5 There also are case reports of treatment of bronchorrhea with octreotide in patients with BAC.