Is malaria confined to equatorial regions?
The warmest climates close to the equator thus have the highest rates of malaria transmission. In effect, this parasitic disease occurs year-round in endemic levels within sub-Saharan Africa, New Guinea and South America.
Does malaria affect liver or spleen?
To conclude, it is known that long-term exposure to malaria causes chronic enlargement of the liver and the spleen and here the levels of three cytokines, IL-12p70, IL-10 and IL-13, and levels of sTNF-RII were found to be associated with both hepatosplenomegaly and exposure to malaria.
What side does malaria affect?
The malaria parasites enter that person’s bloodstream and travel to the liver. When the parasites mature, they leave the liver and infect red blood cells.
Which areas have the highest risk of malaria?
Malaria occurs mostly in poor, tropical and subtropical areas of the world. Africa is the most affected due to a combination of factors: A very efficient mosquito (Anopheles gambiae complex) is responsible for high transmission.
Why is malaria only in tropical areas?
Malaria typically is found in warmer regions of the world — in tropical and subtropical countries. Higher temperatures allow the Anopheles mosquito to thrive. Malaria parasites, which grow and develop inside the mosquito, need warmth to complete their growth before they are mature enough to be transmitted to humans.
What happens to the spleen in malaria?
“The spleen, which often becomes enlarged in malaria, is the main organ that generates the immune response to the malaria parasite and controls the removal of red blood cells that have been infected. This process requires increased production of myeloid cells.”
Which organ is most affected in malaria liver or spleen?
3.2. The inflammatory response in severe malaria-induced ARDS. Beyond the brain, the lungs are the most affected organ in severe malaria.
What climate is best for malaria?
Regions where the climate is ideal for the Anopheles mosquitoes that transmit malaria parasites are more prone to the disease. Anopheles mosquitoes thrive in regions with warm temperatures, humid conditions, and high rainfall. Thus, tropical and subtropical areas are ideal.
Why does the spleen get enlarged in malaria?
Spleen becomes enlarged during malaria because of filtering out of excessive destroyed RBC after the hemolysis and occurs not only during malaria, during many infectious/non infecious diseases following with the RBC hemolysis.
Why does the spleen rupture in malaria?
The spleen plays an important role in malaria, producing antibodies against the malarial parasite. The splenic complications of Plasmodium infection are hematoma, rupture, hypersplenism, ectopic spleen, torsion, cyst, and infarction. Splenomegaly occurs earlier compared to other complications, such as rupture [3,6].
Is spleen affected by malaria?
What is malaria disease?
The Disease. Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness.
What happens if malaria is left untreated?
Malaria is a mosquito-borne disease caused by a parasite. People with malaria often experience fever, chills, and flu-like illness. Left untreated, they may develop severe complications and die. In 2017 an estimated 219 million cases of malaria occurred worldwide and 435,000 people died,…
Can I give blood if I have been in a malaria-transmitted country?
You should tell your health-care provider that you have been traveling in an area where malaria transmission occurs and ask to be tested for malaria infection. Can I give blood if I have been in a country where there is malaria? It depends on what areas of that country you visited, how long ago you were there, and whether you ever had malaria.
What is malaria and how is it spread?
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. It is preventable and curable. In 2018, there were an estimated 228 million cases of malaria worldwide.