Table of Contents
What is metaplasia mean?
(meh-tuh-PLAY-zhuh) A change of cells to a form that does not normally occur in the tissue in which it is found.
Is metaplasia a cancer?
It’s not cancer, but it’s a step toward it. Cells that have transformed once are more likely to transform again. If they go through another stage of transformation, known as dysplasia, they will become precancerous cells.
What is metaplasia and why does it occur?
Metaplasia is the replacement of one differentiated somatic cell type with another differentiated somatic cell type in the same tissue. Typically, metaplasia is triggered by environmental stimuli, which may act in concert with the deleterious effects of microorganisms and inflammation.
What is an example of metaplasia?
metaplasia, in zoology, the conversion of one type of living cell or group of cells into another as a means of regeneration. For example, the damaged or removed lens of a salamander eye is replaced through the transformation of nearby pigmented iris cells into lens cells.
What is metaplasia give example?
Metaplasia is the conversion of one adult tissue type into another, related and more durable, tissue type. The most prevalent examples are conversion of fibrous tissue into bone, or columnar mucosal epithelium into stratified squamous epithelium.
What is difference between dysplasia and metaplasia?
Dysplasia is the presence of abnormal cells within your tissue or one of your organs. Metaplasia is the conversion of one type of cell to another.
Is metaplasia a sequela to cell injury?
Metaplasia, the reversible substitution of one type of fully differentiated cell for another type within a given adult tissue, can also be a sequela to cell injury.
What are the two types of metaplasia?
There are two general types of intestinal metaplasia (type I and II). Metaplastic epithelium that closely resembles normal small intestinal epithelium containing acid mucin-producing goblet cells and absorptive enterocytes with a brush border is considered “complete” (type I).
What is intestinal metaplasia?
Intestinal metaplasia is defined as the replacement of gastric mucinous epithelial cells with small intestinal (goblet, enterocytes, etc.) cells (Fig. 12-11). There are two general types of intestinal metaplasia (type I and II).
How does metaplasia affect the function of normal epithelium?
It can also result in reduced function of the normal epithelium, such as loss of cilia of the respiratory epithelium 1 . Metaplasia occurs due to induction of an alternate differentiation pathway of stem cells.