What category is amitriptyline in pregnancy?
Safety of Psychiatric Medications During Pregnancy and Lactation
| Drug | FDA pregnancy category* |
|---|---|
| Amitriptyline | C |
| Amoxapine (Asendin)‡ | C |
| Clomipramine (Anafranil) | C |
| Desipramine (Norpramin) | C |
Can amitriptyline be used in pregnancy?
Taking amitriptyline in pregnancy would not normally require extra monitoring of your baby. If you have taken amitriptyline around the time of delivery your baby may require extra monitoring after birth because of the possible risk of neonatal withdrawal.
Is TCA teratogenic?
Expert opinion: Although TCAs have been prescribed for several decades, their own teratogenic potential to cause structural defects remains undetermined. However, some signals seem to exist suggesting that prenatal clomipramine exposure may increase the risk of cardiac defects.
Which antidepressant can be used during pregnancy?
Which antidepressants are considered OK during pregnancy? Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft).
Is tricyclic safe during pregnancy?
There are no studies that have shown any antidepressant to be absolutely safe for use during any stage of pregnancy. The use of selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) during pregnancy does not increase the risk of congenital malformations or miscarriage.
Can a woman take antidepressants while pregnant?
Women who take antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), during pregnancy may worry about whether the medications can cause birth defects. There is good news on this front. Osborne says that there is generally no need to taper off medications during pregnancy.
What is pregnancy Category B?
Category B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Does amitriptyline cross the placenta?
Conclusions: Both AMI and NOR cross the human placenta. However, the fetal exposure with NOR may be somewhat smaller compared with AMI, probably due to the higher lipophilicity of AMI.
What is the best antidepressant during pregnancy?
tricyclic antidepressants (TCAs) have been used for many years during pregnancy. The most studied of the selective serotonin re-uptake inhibitors (SSRIs) appears to be fluoxetine (1). Fluoxetine is the only SSRI licensed for use in pregnancy (2).
What antidepressants are safe for pregnant women?
Talk with a therapist on a regular basis
Why is I took antidepressants during my pregnancies?
– Considering continuing, starting, stopping, or switching antidepressant treatment during pregnancy. – Considering reducing the dose of, or discontinuing, antidepressant treatment close to delivery. – The woman is not responding to treatment appropriate to the severity of her depression.
Are antidepressants safe to take during pregnancy?
Yes. A decision to use antidepressants during pregnancy, in addition to counseling, is based on the balance between risks and benefits. The biggest concern is typically the risk of birth defects from exposure to antidepressants.