What does NPPB stand for?

What does NPPB stand for?

NPPB

Acronym Definition
NPPB Natriuretic Peptide Precursor B
NPPB Newbury Park Pony Baseball
NPPB National Plant Pathology Board (American Phytopathological Society)
NPPB National Program for the Prevention of Blindness

Why is BNP called brain?

Later on, a new compound from pig brain was found, which had similar natriuretic and diuretic effects as ANP (Sudoh et al., 1988). This peptide was named brain (B-type) natriuretic peptide (BNP) whose actual site of synthesis is the ventricular myocardium (Mukoyama et al., 1991).

What is the treatment of high BNP?

Treatment with angiotensin-converting enzyme inhibitors, angiotensin-II receptor blockers, spironolactone, and diuretics reduces BNP levels, suggesting that BNP testing may have a role in monitoring patients with heart failure.

What to do if BNP is high?

How to Bring BNP Levels Back to Normal. When levels are above the normal range, doctors usually lower them with medication. Your doctor may prescribe ACE inhibitors, beta-blockers, or diuretics to help.

How do you fix BNP levels?

NPPB, 5-nitro-2- (3-phenylpropylamino)-benzoic acid, is a potent inhibitor of chloride channel with IC50 of 80 nM for the short circuit current. [1]

What is the mechanism of action of NPPB?

NPPB (5-nitro-2- (3-phenylpropylamino)benzoic acid) has been reported to block Cl- channels in isolated rabbit nephrons with high potency (IC50 = 80 nM).

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What is the activity of NPPB in short circuit?

NPPB was evaluated for the activity on the equivalent short circuit current, corresponding to the secondary active transport of Cl- and measurements of the voltage across the basolateral membrane. The result revealed that NPPB possessed a good potency with IC50 of 80 nM for inhibiting the short circuit current.