Is dysgerminoma malignant or benign?
Dysgerminoma: This is the most common type of malignant ovarian germ cell tumor. Mature teratoma (dermoid cyst or ovarian cyst): This is the most common type of benign ovarian germ cell tumor. These noncancerous tumors usually grow in teenage girls and young women.
Is dysgerminoma a cancer?
A type of cancer that begins in germ cells in females. Germ cells are cells that form sperm in males or eggs in females. Dysgerminomas occur most often in the ovaries, but they may also occur in other areas of the body, including the central nervous system.
Which tumor marker is raised in dysgerminoma?
Serum lactic dehydrogenase as a tumor marker in dysgerminoma.
What is the tumor marker for dysgerminoma?
The standard workup for suspected dysgerminomas includes the following tumor markers: Lactate dehydrogenase (LDH) Beta-human chorionic gonadotropin (beta-hCG) Alpha-fetoprotein (AFP)
What is the treatment for dysgerminoma?
Treatment of dysgerminoma may be either: total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by radiation therapy or combination chemotherapy; or. unilateral salpingo-oophorectomy followed by chemotherapy.
What causes dysgerminoma?
Dysgerminoma: This slow-growing cancer begins in female germ cells and causes dysregulation of the hormone beta-human chorionic gonadotropin (beta-hCG), which the body produces at higher levels when pregnant. Dysgerminoma is the most common type of ovarian germ cell tumor.
What is an ovarian dysgerminoma?
Ovarian dysgerminomas are a type of germ cell tumor of the ovary. They are the most common malignant germ cell tumors of the ovary and are thought to account for ~1% of all ovarian neoplasms 5. They are rare ovarian tumors that occur predominantly in young women (majority occurring in the 2 nd to 3 rd decades 5 ).
What are yolk sac tumors (endodermal sinus tumors)?
Yolk sac tumors (also known as endodermal sinus tumors) are malignant primitive germ cell tumors; they are histologically similar to the mesenchyma of the primitive yolk sac. Yolk sac tumors can be found in a pure form or mixed with other germ cell tumors. They are common in the pediatrics age group and can be found anywhere in the body.
What are the different types of ovarian germ cell tumors?
The most common types of ovarian germ cell tumors are: Dysgerminoma: This is the most common type of malignant ovarian germ cell tumor. Mature teratoma (dermoid cyst or ovarian cyst): This is the most common type of benign ovarian germ cell tumor. These noncancerous tumors usually grow in teenage girls and young women.
What is dysgerminoma with H&E stain?
Micrograph of a dysgerminoma, H&E stain. A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary . A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis or germinoma in the central nervous system or other parts of the body.