What is seminomas and Nonseminomas?
Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. Nonseminoma tumors are often made up of more than one type of cell, and are identified according to these different cell types: Choriocarcinoma (rare) Embryonal carcinoma.
Is Leydig cell tumor a seminoma?
Seminomas are more common and occur in 30–40% of testicular tumors. Leydig cell tumors are derived from undifferentiated gonadal mesenchyme and the concurrent development of the tumor and a seminoma which are derived from germinal epithelium in an ipsilateral testis is extremely rare.
What is Spermatocytic tumor?
Spermatocytic tumor is a rare malignancy that accounts for 0.61% of testicular germ cell tumors[1]. Tumor development is independent of ethnicity and a history of cryptorchidism. Older men with an average age of 52 years are often the most affected[2].
Which tumor is the most aggressive of testicular cancers?
Embryonal carcinoma: present in about 40 percent of tumors and among the most rapidly growing and potentially aggressive tumor types. Embryonal carcinoma can secrete HCG or alpha fetoprotein (AFP).
Is Spermatocytic tumor malignant?
Spermatocytic tumor is a rare, malignant neoplasm of the testes. Since the prognosis for this tumor type is favorable, accurate diagnosis and differentiation from other malignant testicular neoplasms (classic seminoma and lymphoma) are crucial.
What is Itgcn?
Intratubular germ cell neoplasia (ITGCN) is the precursor lesion for invasive testicular germ cell tumors (TGCTs) of adolescents and young adults. The rising incidence of these tumors has prompted a rigorous investigation of the etiology, diagnosis and management of ITGCN.
Is non seminoma malignant?
Testicular non-seminomatous giant cell tumor (NSGCT) is curable cancer. It can be managed ideally if the medical health providers know the knowledge of its pathophysiology and route of spread. It is a malignant but curable tumor if diagnosed and managed properly.
What is Leydig cell tumour?
Jump to navigation Jump to search. Leydig cell tumour, also Leydig cell tumor (US spelling), (testicular) interstitial cell tumour and (testicular) interstitial cell tumor (US spelling), is a member of the sex cord-stromal tumour group of ovarian and testicular cancers. It arises from Leydig cells.
What are the immunohistochemical markers of Leydig cell tumor?
Immunohistochemical markers of Leydig cell tumours include inhibin-alpha, calretinin, and melan-A. The usual chemotherapy regimen has limited efficacy in tumours of this type, although imatinib has shown some promise. There is no current role for radiotherapy.
Which specialist consultations are beneficial to patients with Leydig cell tumor (LCT)?
Likewise, primary care providers or endocrinologists should consider Leydig cell tumors in the differential diagnosis of infertility, hypogonadism, and especially gynecomastia.
Can ultrasound detect Leydig tumours?
However, hormonal disturbances, in Leydig tumours, is present in only 2/3 of cases. Testicular Leydig cell tumours can be detected sonographically, ultrasound examinations may be ordered in the event of a palpable scrotal lump, however incidental identification of these lesions is also possible.