What is the organ of Zuckerkandl?
The organ of Zuckerkandl is a chromaffin body derived from neural crest located at the bifurcation of the aorta or at the origin of the inferior mesenteric artery. It can be the source of a paraganglioma. The abdominal aorta and its branches.
Where are paragangliomas located?
Paraganglioma is a type of neuroendocrine tumor that forms near certain blood vessels and nerves outside of the adrenal glands. The adrenal glands are important for making hormones that control many functions in the body and are located on top of the kidneys.
Where do pheochromocytomas grow?
About 80-85% of pheochromocytomas grow in the inner layer of the adrenal gland, called the adrenal medulla. About 15-20% of pheochromocytomas grow outside of this area and are called extra-adrenal pheochromocytomas or paragangliomas.
Where is the inferior mesenteric artery?
The inferior mesenteric artery (IMA) is another major blood supply to the lower GI tract (Fig. 25.4). It is located at the level of L2-L4 (most often at the L3-L4 disk space level, 2–3 cm above the aortic bifurcation). The IMA supplies the distal transverse colon, descending colon, sigmoid colon, and rectum.
Are all pheochromocytomas malignant?
Approximately 10% of pheochromocytomas (with a range of 3–50% according to different studies) are considered to be malignant [5]. There are no reliable histological features allowing a distinction of a benign from a malignant tumor.
What is a paraganglioma carotid body?
A carotid body tumor (also called a chemodectoma or paraganglioma) is a growth on the side of your neck in the area where the carotid artery splits off into smaller blood vessels that carry blood to your brain.
What organs does the superior mesenteric artery serve?
The superior mesenteric artery provides blood to the:
- Pancreas.
- Small intestine, including the duodenum (part that connects the small intestine to the stomach).
- Large intestine.
What organs do the mesenteric arteries serve?
The superior mesenteric artery supplies the midgut from the ampullary region of the second part of the duodenum to the splenic flexure of the large intestine. The inferior pancreaticoduodenal artery arises from the SMA and, along with the superior pancreaticoduodenal artery, supplies the head of the pancreas.
What organs does the superior mesenteric artery supply?
Is a paraganglioma a brain tumour?
What is a paraganglioma? A paraganglioma is a type of tumour that arises from the peripheral nervous system (part of the nervous system outside the brain and spinal cord), which is further divided into the sympathetic nervous system and the parasympathetic nervous system.
What is the cause of carotid body tumor?
What Causes a Carotid Body Tumor? In most patients with a carotid body tumor, there is no known cause except for hypoxia (the chronic oxygen deprivation that may come from living at high altitudes). In a smaller percentage of patients there is a family connection.
What is the pathophysiology of Zuckerkandl tumor?
The organ of Zuckerkandl is of pathological significance in the adult as a common extra-adrenal site of pheochromocytoma though the most common extra-adrenal site is in the superior para-aortic region between the diaphragm and lower renal poles. Extra-adrenal tumors account for around 25% of all cases of pheochromocytoma.
Organ of Zuckerkandl. Dr Daniel J Bell ◉ and Dr Bruno Di Muzio ◈ et al. The organ of Zuckerkandl comprises of a small mass of chromaffin cells derived from neural crest located along the aorta, beginning cranial to the superior mesenteric artery or renal arteries and extending to the level of the aortic bifurcation or just beyond.
What is the history of Zuckerkandl disease?
It was first described in 1901 by Emil Zuckerkandl (1849-1910) 4, a professor of anatomy at the University of Vienna. 1. Saurborn DP, Kruskal JB, Stillman IE et-al. Best cases from the AFIP: paraganglioma of the organs of Zuckerkandl.
What is paraganglioma of the neck?
Paragangliomas are tumors of the sympathetic and parasympathetic paraganglia. While most paraganglioma are of parasympathetic origin and present as benign palpable masses of the neck, sympathetic paraganglioma are often secretory, presenting with symptoms related to excess catecholamines.