What is the drug meprobamate used for?
Meprobamate is used to relieve nervousness or tension. This medicine should not be used for nervousness or tension caused by the stress of everyday life. Meprobamate is available only with your doctor’s prescription.
What is the Iupac name of meprobamate?
Meprobamate
| Clinical data | |
|---|---|
| IUPAC name [2-(carbamoyloxymethyl)-2-methyl-pentyl] carbamate | |
| CAS Number | 57-53-4 |
| PubChem CID | 4064 |
| IUPHAR/BPS | 7225 |
Is meprobamate a depressant?
meprobamate, drug used in the treatment of anxiety. A central nervous system depressant, meprobamate acts selectively upon the spinal cord and the higher centres in the brain. Physical dependence may be produced after utilization of high doses for prolonged periods.
What type of drug is meprobamate?
Meprobamate is used to treat anxiety disorders or for short-term relief of the symptoms of anxiety in adults and children 6 years of age and older. Meprobamate is in a class of medications called tranquilizers. It works by slowing activity in the brain to allow for relaxation.
What are the effects of meprobamate?
Common side effects of meprobamate may include: bruising; numbness or tingling; blurred vision; or. nausea, vomiting, diarrhea.
What class of drug is meprobamate?
Meprobamate is in a class of medications called tranquilizers. It works by slowing activity in the brain to allow for relaxation.
What is the molecular formula of meprobamate?
C9H18N2O4Meprobamate / Formula
Is meprobamate a muscle relaxant?
meprobamate [m-pro′b-māt mep″ro-bam′āt] a carbamate derivative used as a tranquilizer and skeletal muscle relaxant.
What is meprobamate metabolite?
Meprobamate (2-methyl-2-propyl-trimethylene dicarbamate; Fig. 6.8) is a mild tranquilizer, which has been used since the early 1950s. It is also a metabolite of the centrally acting muscle relaxant carisoprodol.
Are barbiturates the same as benzodiazepines?
Introduction. Two of the major drug classes that can inhibit central nervous system (CNS) activity are benzodiazepines and barbiturates. Although benzodiazepines have largely replaced the older barbiturates in clinical and recreational use, both drug classes share similarities and are of toxicological relevance.
Is meprobamate an NSAID?
Why is Meprobamate and Aspirin Prescribed? (Indications) This combination medication contains a non-steroidal anti-inflammatory drug (NSAID) and an anxiolytic, prescribed for pain with anxiety or tension from muscle/bone problems.
Is meprobamate acidic or basic?
Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated)….3D Structure for HMDB0014515 (Meprobamate)
| Property | Value | Source |
|---|---|---|
| logS | -2 | ALOGPS |
| pKa (Strongest Acidic) | 15.17 | ChemAxon |
| Physiological Charge | 0 | ChemAxon |
Is meprobamate an Nsaid?
Why benzodiazepines are preferred over barbiturates?
Benzodiazepines and the newer non-benzodiazepine hypnotics are now preferred over barbiturates for most of these clinical uses because they have a wider therapeutic index, tolerance develops more slowly, and their liability for abuse is lower than that of the barbiturates.
What is the mechanism of action of meprobamate?
Although the exact mechanism of meprobamate is largely unknown, it appears to act as a depressant at multiple sites in the central nervous system, mostly likely through the GABAergic neurotransmitter system, including the thalamus and limbic system.
How do you make meprobamate dicarbamate?
Meprobamate, 2-methyl-2-propyl-1,3-propandiol dicarbamate is synthesized by the reaction of 2-methylvaleraldehyde with two molecules of formaldehyde and the subsequent transformation of the resulting 2-methyl-2-propylpropan-1,3-diol into the dicarbamate via successive reactions with phosgene and ammonia.
Is meprobamate a Schedule 4 drug?
Meprobamate is a Schedule IV drug (US) (S5 in South Africa) under the Convention on Psychotropic Substances. With protracted use, it can cause physical dependence and a potentially life-threatening abstinence syndrome similar to that of barbiturates and alcohol (delirium tremens).
Is meprobamate a barbiturate?
Meprobamate, like barbiturates, possesses an analgesic/anesthetic potential. It is also found as a component of the combination analgesic Stopayne capsules (along with paracetamol (acetaminophen), caffeine, and codeine phosphate).