Do you give EPI SUBQ or IM?
The product label of EpiPen, the only autoinjection epinephrine product approved in the US for anaphylaxis, recommends IM intramuscular injection into the anterolateral aspect of the thigh, but it also states that epinephrine, when given intramuscularly or subcutaneously, has a rapid onset of action, which supports …
Can epinephrine be given IM?
Intramuscular epinephrine injection (preferred) — Intramuscular (IM) injection is the preferred route for initial administration of epinephrine for anaphylaxis in most settings and in patients of all ages (table 3) [37,38].
Why is adrenaline not given subcutaneously?
The subcutaneous route for adrenaline is not recommended for treatment of an anaphylactic reaction as it is less effective.
What is the difference between SUBQ and im injections?
Intramuscular injections are absorbed faster than subcutaneous injections. This is because muscle tissue has a greater blood supply than the tissue just under your skin. Muscle tissue can also hold a larger volume of medication than subcutaneous tissue.
How do you administer epinephrine IM?
The intramuscular injection is given into the mid-outer thigh. If using an autoinjector, it should be held in place for three seconds after the injection, which is sufficient to deliver the dose. Most patients respond to a single dose of intramuscular epinephrine.
How should epinephrine be administered?
This medicine is injected under the skin or into the muscle of your outer thigh only. Do not inject this medicine into a vein, into the muscle of your buttocks, or into your fingers, toes, hands, or feet. To do so, may increase the chance of having serious side effects.
Can EpiPen be given subcutaneously?
Epipen (epinephrine injection) is given as an intramuscular (in the muscle) or subcutaneous (under the skin) injection only in the middle of the outer side of the thigh (the upper leg). It can be injected through clothing if needed.
What is subcutaneous epinephrine used for?
This medication is used in emergencies to treat very serious allergic reactions to insect stings/bites, foods, drugs, or other substances. Epinephrine works quickly to improve breathing, stimulate the heart, raise a dropping blood pressure, reverse hives, and reduce swelling of the face, lips, and throat.
Why are drugs given subcutaneously?
Subcutaneous injection can be used to give many types of medications for various medical conditions. There are fewer blood vessels in the fatty layer of connective tissue just beneath the skin than the muscle tissue. Having fewer blood vessels means that medication injected subcutaneously is absorbed more slowly.
Where do you inject IM epinephrine?
What routes can epinephrine be given?
The various recommended routes of epinephrine administration include intravenous, intramuscular or subcutaneous injection, and inhalation from a metered-dose inhaler [4–16,22–24].
Where do I give EPI IM?
What are the advantage of subcutaneous route?
The main advantage of a subcutaneous transposition is that it is easy to perform. It is a good procedure when subluxation and traction on the nerve are contributing to the patient’s symptoms. The primary disadvantage is that the nerve may be hypersensitive after surgery because of its new superficial location.
What is the advantage of subcutaneous injection?
Subcutaneous infusion systems can be designed with smaller needle sizes, which may decrease pain during infusion. While the risk of infusion site infection still exists with SC administration, infusion site infections are generally limited to cellulitis and very rarely progress to systemic infections.
Why is subcutaneous injection slow?
There are fewer blood vessels in the fatty layer of connective tissue just beneath the skin than the muscle tissue. Having fewer blood vessels means that medication injected subcutaneously is absorbed more slowly.
What is the difference between subcutaneous intramuscular and intravenous injection?
The subcutaneous tissue layer is the injection site of subcutaneous injection, while a muscle is the injection site of intramuscular injection. The site of intravenous injection, on the other hand, is a vein. So, this is the key difference between subcutaneous intramuscular and intravenous injection.
Does intramuscular injection increase plasma epinephrine concentration?
Peak plasma epinephrine concentrations were significantly higher (P < .01) after epinephrine was injected intramuscularly into the thigh than after epinephrine was injected intramuscularly or subcutaneously into the upper arm.
What is the preferred route and site of injection of epinephrine?
We recommend intramuscular injection of epinephrine into the thigh as the preferred route and site of injection of this life-saving medication in the initial treatment of anaphylaxis.
What is the difference between epinephrine 1-1000 and 1-10000?
Epinephrine injection 1:1000 is equivalent to 1 mg/mL and epinephrine injection 1:10,000 is equivalent to 0.1 mg/mL. * available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name