What is small round blue tumor?
Neuroblastoma is a classic “small round blue cell” tumor. Others include Ewing sarcoma, non-Hodgkin lymphoma, primitive neuroectodermal tumors, and rhabdomyosarcoma.
What are small round cell tumors?
Desmoplastic small round cell tumors, or DSRCT, are tumors that grow in the abdomen and pelvic area of the body. Desmoplastic small round cell tumors are a type of soft tissue sarcoma, which is a type of cancer that forms in the connective tissue of the body.
What is a blue cell tumour?
In histopathology, a small-blue-round-cell tumour (abbreviated SBRCT), also known as a small-round-blue-cell tumor (SRBCT) or a small-round-cell tumour (SRCT), is any one of a group of malignant neoplasms that have a characteristic appearance under the microscope, i.e. consisting of small round cells that stain blue on …
What are round blue cell tumors?
Small round blue cell tumor: a group of childhood tumors that is characterized by a similar appearance under the microscope. The appearance is that of small, round, primitive cells that stain blue with conventional staining techniques for biopsy analysis.
How many types of rhabdomyosarcoma are there?
There are four main types of rhabdomyosarcoma: Embryonal: This type occurs most often in the head and neck area or in the genital or urinary organs, but can occur anywhere in the body. It is the most common type of rhabdomyosarcoma.
What are blue cells called?
What are desmoplastic small round cell tumors? Desmoplastic small round cell tumors (DSRCTs, sometimes also referred to as small blue round cell tumor) are a type of sarcoma that usually develops in the belly or pelvis. They are most often found in white teenagers and young men between age 10 and 30.
What is the most common type of rhabdomyosarcoma?
Embryonal rhabdomyosarcoma is the most common type of rhabdomyosarcoma. It can form in the head and neck area, or in the genital or urinary organs.
What is a ‘small round blue cell’ tumor?
One such area is the ‘small round blue cell’ tumor category. This group of tumors encompasses a wide diversity of both benign and malignant neoplasms.
What does a sinonasal tract tumor with spindles with no cartilage look like?
There is a small round blue cell to spindled appearance without well-developed cartilage (a), although neoplastic hyaline cartilage is surrounded by a small round blue cell component in this sinonasal tract tumor (b).
What is the best marker for small round blue cell carcinoma?
One of the most helpful markers is strong nuclear expression for SOX9, a regulator of chondrogenesis, non-reactive in the other small round blue cell tumors. 23, 24 Further, about 80% of tumors show HEY1 – NCOA2 fusions by FISH. 25
Can 5b14 Mab be used to diagnose small round cell tumours?
The 5B14 mAb represents an additional tool for the differential diagnosis of small round cell tumours and might be useful in identifying neuroblastoma patients at risk of relapse who may take advantage of more careful follow-up. Keywords: B7-H3, diagnosis, neuroblastoma, small round cell tumours Introduction