Table of Contents
What does Malassezia globosa do?
Malassezia yeasts are skin commensals that can also be involved in the pathogenesis of Malassezia folliculitis, dandruff and seborrhoeic dermatitis. They may cause aggravation of atopic dermatitis and psoriasis on the head and neck.
Does everyone have Malassezia globosa?
Malassezia globosa is a fungus present on the skin of many newborns. Often, it lives harmlessly in the top layer of skin without causing any problems. But for an estimated 50% of the population, it burrows into a hair follicle and sets up shop.
What is the best antifungal for Malassezia?
also showed high MIC values for ketoconazole, which is the most widely recommended topical antifungal to treat Malassezia skin infections.
Does Malassezia feed on sugar?
Unlike other yeasts that use sugars as their food source (Saccharomyces and Candida) Malassezia feeds on fats. Because Malassezia depends on fats rather than sugars and because it lives on the skin, NOT in the intestines, it is unaffected by sugars and carbohydrates that are consumed in the diet.
What is the role of Malassezia globosa in the pathogenesis of pityriasis versicolor?
Different species of Malassezia obviously play a role in the development of disease, although it is not known why, for instance, M. globosa in particular should be associated with pityriasis versicolor.
What is Malassezia versicolor?
Malassezia species dominate the skin fungal microbiome in core scalp, body, and arm sites of adults.51a The infection is associated with transformation of yeast-phase organisms into hyphal forms, although occasional patients with pityriasis versicolor have only oval yeasts.
What is the role of M globosa in dermatology?
M. globosa has also been implicated in other skin conditions, such as sweat allergy. It releases MGL_1304, a 17-kDa protein that acts as an antigen for the release of high levels of histamine. It also plays a role, along with other species of Malassezia, in pityriasis versicolor and atopic eczema.
What is Malassezia folliculitis?
This disease is caused by the yeast Malassezia species, most commonly by Malassezia globosa. Malassezia yeasts are skin commensals that can also be involved in the pathogenesis of Malassezia folliculitis, dandruff and seborrhoeic dermatitis. They may cause aggravation of atopic dermatitis and psoriasis on the head and neck.