Table of Contents
What is the most common disease caused by Propionibacterium?
Affiliations. Propionibacterium acnes is a gram-positive human skin commensal that prefers anaerobic growth conditions and is involved in the pathogenesis of acne (Kirschbaum and Kligman, 1963). Acne is one of the most common skin diseases, affecting more than 45 million individuals in the United States.
What is Propionibacterium Avidum?
Propionibacterium avidum: A Virulent Pathogen Causing Hip Periprosthetic Joint Infection | Clinical Infectious Diseases | Oxford Academic.
How do you treat Cutibacterium Avidum?
A long-term treatment regimen with a combination of antibiotics is required to successfully eliminate the remaining adherent bacteria, particularly in the case of deep infections after debridement surgery.
Where does Propionibacterium come from?
Propionibacterium acnes is a bacterium commonly found on the skin, in pores and hair follicles. These bacteria play an important part in acne. Their role, though, is more positive than was for a long time thought. Propionibacterium acnes is a bacterium commonly found on the skin, in pores and hair follicles.
Where is Propionibacterium acnes most commonly found?
Propionibacterium acnes is the most abundant bacterium on human skin, particularly in sebaceous areas.
Where is Propionibacterium acnes most likely to be found?
the skin
Propionibacterium acnes is a bacterium commonly found on the skin, in pores and hair follicles. These bacteria play an important part in acne. Their role, though, is more positive than was for a long time thought. Propionibacterium acnes is a bacterium commonly found on the skin, in pores and hair follicles.
What are the symptoms of Propionibacterium acnes?
For low-grade P. acnes shoulder infections, pain may be the only symptom, followed by stiffness with all other signs of infection being absent (12). Periprosthetic joint infections can be extremely serious and may result in loss of normal function of the joint or even progress to sepsis (6).
Does ceftriaxone cover Cutibacterium?
Ceftriaxone treatment of spondylodiscitis and other serious infections with Cutibacterium acnes. J Antimicrob Chemother.
What does Propionibacterium cause?
Although primarily recognized for its role in acne, P. acnes is an opportunistic pathogen, causing a range of postoperative and device-related infections. These include infections of the bones and joints, mouth, eye and brain.
What is Propionibacterium acnes route of infection?
SUMMARY. Propionibacterium acnes is known primarily as a skin commensal. However, it can present as an opportunistic pathogen via bacterial seeding to cause invasive infections such as implant-associated infections.
Where specifically on the body would you find Propionibacterium acnes?
Propionibacterium acnes is a facultative anaerobic Gram-positive bacterium present on human skin as part of the normal flora, as well as in the oral cavity, large intestine, conjunctiva, and external ear canal (1).
How is Propionibacterium acnes spread?
An under-recognized pathogen Propionibacterium acnes, or P. acnes, live in hair follicles — the tiny pores in our skin from which hairs sprout. When these pores become blocked, the bacteria can multiply and contribute to the inflammation we call acne.
What causes P. acnes bacteria?
Cascade of chemicals The airless environment causes the bacterium, Propionibacterium acnes, to turn sebum – an oily matter found in the skin – into fatty acids that activate inflammation in nearby skin cells.
Does ceftriaxone cover P. acnes?
Antibiotics with the lowest MIC values against P. acnes (MIC50 and MIC90) included penicillin G (0.006, 0.125), cephalothin (0.047 and 0.094), and ceftriaxone (0.016, 0.045), while others also showed activity.
Where is Propionibacterium found?
Propionibacterium acnes is a Gram-positive bacterium that forms part of the normal flora of the skin, oral cavity, large intestine, the conjunctiva and the external ear canal.
What are symptoms of Propionibacterium acnes?
Deeper infection with P. acnes are often subtle and difficult to diagnose with subacute infection being the common presentation. Pain, stiffness, and implant loosening can be presenting symptoms.
How does Propionibacterium acnes spread?
What does Propionibacterium acnes cause?
Propionibacterium acnes Infection P. acnes is a gram-positive commensal bacterium that causes acne on the skin. P. acnes releases lipase that produces fatty acids by digesting sebum, creating inflammation of the skin.
Does Propionibacterium avidum cause prosthetic joint infections (PJIs)?
Propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (PJIs). Other Propionibacterium spp. have occasionally been described as a cause of PJIs, but this has not previously been the case for P. avidum despite its capacity to form biofilm.
How are prosthetic hip joint infections caused by Pseudomonas avidum treated?
We describe two patients with prosthetic hip joint infections caused by P. avidum. Both patients were primarily operated with an anteriorly curved skin incision close to the skin crease of the groin, and both were obese. Initial treatment was performed according to the DAIR procedure (debridement, antibiotics, and implant retention).
Is the ratio of biofilm to total mass different in Propionibacterium avidum strains?
The ratio of biofilm to total mass of the P. avidum strains was, however, not significantly different from the P. acnes strain ATCC 11827 ( Figure 3B ). Figure 3. Phenotypic characterization of Propionibacterium avidum strains isolated in 2015 from hip prosthetic joint infections (PJIs) (clinical isolates 828, 853, 878, 882).
How is Propionibacterium avidum (PJI) diagnosed?
a Diagnosis of P. avidum PJI was based on clinical presentation of sinus tract as well as previous growth of P. avidum in another hospital. Table 2. Diagnostic Characteristics of 12 Patients With Prosthetic Joint Infection Caused by Propionibacterium avidum at Time of Septic Surgery at the University Hospital Balgrist .