How serious is metastatic squamous cell carcinoma?

How serious is metastatic squamous cell carcinoma?

The prognosis for cutaneous SSC after definitive treatment is generally good, with three-year disease-specific survival of around 85% [5]. Metastasis of cutaneous squamous cell carcinoma (cSCC) is rare. However, certain tumor and patient characteristics increase the risk of metastasis.

What is metastatic squamous neck cancer?

Metastatic squamous neck cancer with occult primary is a disease in which squamous cell cancer spreads to lymph nodes in the neck and it is not known where the cancer first formed in the body. Signs and symptoms of metastatic squamous neck cancer with occult primary include a lump or pain in the neck or throat.

Is squamous neck cancer curable?

Associated Data. More than 90% of tumours in the head and neck are squamous carcinomas. Cancer of the head and neck, which can arise in several places, is often preventable, and if diagnosed early is usually curable.

Where do head and neck cancers metastasize?

The most common sites of distant metastases were the lungs (70%), the liver (42%), and the bones (15%).

What is the survival rate for metastatic squamous cell carcinoma?

Survival. Three-year, disease-free survival rates following surgery and/or radiation therapy for unknown squamous primaries range from 40% to 50% in patients with N1 disease, to 38% and 26% for patients with N2 and N3 disease, respectively.

What is the prognosis for squamous cell cancer of the throat?

Prognosis of Throat cancer (Squamous Cell Carcinoma of the Tonsil) Early cancer of the throat detected incidentally is associated with a good prognosis. Involvement of lymph nodes in the region is associated with a poorer throat cancer prognosis. 5 year survival in early cases is more than 90%.

Can you survive metastatic squamous cell carcinoma?

The prognosis of patients with recurrent or metastatic head and neck squamous cell cancer is generally poor. The median survival in most series is 6 to 15 months depending on patient- and disease-related factors. Symptom-directed care plays an important role in the management of these patients.

Is squamous cell cancer fatal?

Untreated squamous cell carcinoma of the skin can destroy nearby healthy tissue, spread to the lymph nodes or other organs, and may be fatal, although this is uncommon. The risk of aggressive squamous cell carcinoma of the skin may be increased in cases where the cancer: Is particularly large or deep.