Why was Cafergot discontinued?

Why was Cafergot discontinued?

Cafergot contains ergotamine as its active ingredient, mixed with caffeine to aid absorption. Medsafe Group Manager Chris James says the medicine has dated and limited evidence of effectiveness and recent more extensive evidence of adverse events – including fibrosis or internal scarring.

What is the side effect of Cafergot?

Nausea, vomiting, upset stomach, restlessness, trouble sleeping, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Can you take ergotamine everyday?

Ergotamine is used only when needed and does not have a daily dose. Do not take more than 3 tablets per day or 5 tablets per week.

Who can take Cafergot?

Cafergot is not recommended in patients aged under 12 years or over 65 years. Cafergot is only indicated for the treatment of acute migraine attacks and not for prevention. Continued daily use of Cafergot or it’s use in excess of the recommended doses must be avoided since it may cause vasospasm.

Is there a generic version of Cafergot?

Cafergot may be available in generic form. Common side effects of Cafergot include nausea, vomiting, upset stomach, restlessness, trouble sleeping, dizziness, spinning sensation, weakness, or itching. Dosage of Cafergot should start at the first sign of an attack.

Does Cafergot affect lactation?

Ergot drugs are known to inhibit prolactin but there are no reports of decreased lactation with Cafergot. Ergotamine is excreted in breast milk and may cause symptoms of vomiting, diarrhea, weak pulse and unstable blood pressure in nursing infants.

What is Cafergot used to treat?

Indications and Usage for Cafergot Cafergot® (ergotamine tartrate and caffeine) Indicated as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants or so-called “histaminic cephalalgia”.

Can You overdose on Cafergot ® (ergotamine tartrate)?

The toxic effects of an acute overdosage of Cafergot ® (ergotamine tartrate and caffeine) are due primarily to the ergotamine component. The amount of caffeine is such that its toxic effects will be overshadowed by those of ergotamine.