Table of Contents
What is granulator used for?
Granulators are essentially rotary grinders that are used to grind scrap parts and melt delivery systems (sprues and runners) into feedstock sized granules for reprocessing. This allows the molder to reduce waste and produce components more cost effectively.
What is wet granulator used for?
Wet granulation is a widely used process in the pharmaceutical industry since this improves the flow properties, homogeneity and compressibility of the powder mix. Fluidized bed granulators and high shear mixers are typically used in traditional batch wet granulation processes.
What is granulation theory?
Granulation is the process in which primary. powder particles are made to adhere to form. larger, multiparticle entities called granules. Pharmaceutical granules typically have a size range. between 0.2 and 4.0 mm, depending on their subsequent.
Which granulator is used for dry granulation?
Roller compactors commonly referred to as chilsonator is a dry granulating equipment that produces a sheet of powder material by squeezing powder between two rollers.
How does a tumbling granulator work?
In tumbling granulators, particles are set in motion by the tumbling action caused by the balance between gravity and centrifugal forces. These granulators have the following characteristics: Product granule size is in the range 2 to 20 mm. Tumbling granulators are not suitable for producing very small granules.
How many types of granulation are there?
Two types
Unless the powdered sugar is granulated, it could not efficiently be made into a tablet that has good tablet characteristics such as uniform content or consistent hardness. Two types of granulation technologies are employed: wet granulation and dry granulation.
What is slugging in granulation?
Slugging is a pre-compression process for the formation of extra large tablets (slugs), usually of variable weight, due to poor flow of the drug powder. The resulting slugs are subsequently broken down into granules, which are recompressed to obtain the final tablets.
What is the end point of RMG?
Endpoint can be defined as a target particle size mean or distribution. a) Power Consumption. Power consumption of the mixer motor for end-point determination and scale-up is widely used because the measurement is economical, does not require extensive mixer modifications and is well correlated with granule growth.
What is the use of purging air in RMG?
What is Purging Air in RMG? Generally, purging air is used to flush the industrial process equipment with clean air. Purging Air helps to keep the surfaces of RMG (Granulation Machine) clean and help in maintaining its effective performance.
Why is a tablet binder necessary for granulation?
Tablet binders are one of the most essential elements in the formulation of a tablet. Because they promote cohesiveness, the binders, also called adhesives, help the other ingredients in a tablet to mix together. Tablet binders are used to turn powder to granules; this is achieved through the process of granulation.
Why is slugging in dry granulation?
Slugging (Traditional approach) It is the cheapest method of granulation and is suitable for heat and moisture sensitive products. In this method, the mixture of powders are compressed into slugs on specially designed tablet machines without using heat and solvent followed by milling the compact mass into granules.
Can you use Vaseline for slugging?
Many people have used slugging to obtain plump skin at home, because it only requires one product. All you need is a thick, ointment-based moisturizer like Vaseline, Aquaphor, CeraVe Healing Ointment or Cetaphil Healing Ointment.