What is extrapyramidal symptoms PPT?
Extrapyramidal symptoms. These symptoms include dystonia (continuous spasms and muscle contractions), akathisia (motor restlessness), parkinsonism (characteristic symptoms such as rigidity), bradykinesia (slowness of movement), and tremor, and tardive dyskinesia (irregular, jerky movements).
What drugs cause EPS?
Extrapyramidal symptoms are most commonly caused by typical antipsychotic drugs that antagonize dopamine D2 receptors. The most common typical antipsychotics associated with EPS are haloperidol and fluphenazine.
What is the extrapyramidal system?
The extrapyramidal system is the name used to describe a number of centers and their associated tracts whose primary function is to coordinate and process motor commands performed at a subconscious level.
Why do anticholinergics treat EPS?
When anticholinergic agents, such as benztropine, are given to relieve EPS, the intention is to block the excessive nigrostriatal acetylcholine transmission that ultimately causes the motor side effects.
Which brain region is involved in extrapyramidal effects?
Extrapyramidal tracts: Originate in the brainstem, carrying motor fibres to the spinal cord. They are responsible for the unconscious, reflexive or responsive control of musculature, eg muscle tone, balance, posture and locomotion.
What drugs treat EPS?
Management of EPS
| Type of Later EPS | Treatment |
|---|---|
| Neuroleptic-induced parkinsonism | Stop or reduce the dosage of causative medication. Switch to an atypical antipsychotic. Anti-parkinson medications: Amantadine, Antimuscarinic agents, Dopamine agonists, Levodopa |
What is EPS and its types?
Reported EPS or GAAP EPS is the earnings figure derived from generally accepted accounting principles (GAAP). Ongoing or pro forma EPS excludes unusual one-time company gains or losses. Carry value or book value EPS is the real cash worth of each share of company stock.
What is extrapyramidal function?